Evidence map›Paper›PMID 32587574›Full record

ArticleFrontiers in endocrinology2020

Partial Body Mass Recovery After Caloric Restriction Abolishes Improved Glucose Tolerance in Obese, Insulin Resistant Rats.

Manuel A Cornejo, Julie Nguyen, Joshua Cazares, Benny Escobedo, Akira Nishiyama, Daisuke Nakano, Rudy M Ortiz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Manuel A CornejoSchool of Natural Sciences, University of California, Merced, Merced, CA, United States.
Julie NguyenSchool of Natural Sciences, University of California, Merced, Merced, CA, United States.
Joshua CazaresSchool of Natural Sciences, University of California, Merced, Merced, CA, United States.
Benny EscobedoSchool of Natural Sciences, University of California, Merced, Merced, CA, United States.
Akira NishiyamaDepartment of Pharmacology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Daisuke NakanoDepartment of Pharmacology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
Rudy M OrtizSchool of Natural Sciences, University of California, Merced, Merced, CA, United States.
University of California, Merced · USKagawa University · JP

Funding

UCSC MHIRT Research Training GrantT37MD001480 · NIMHD · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ORTIZ, CHARLES L · 2005 to 2018
$3.4M
NIMHD NIH HHS T37 MD001480
6 · The paper itself

Abstract

Caloric restriction, among other behavioral interventions, has demonstrated benefits on improving glycemic control in obesity-associated diabetic subjects. However, an acute and severe intervention without proper maintenance could reverse the initial benefits, with additional metabolic derangements. To assess the effects of an acute caloric restriction in a metabolic syndrome model, a cohort of 15-week old Long Evans Tokushima Otsuka (LETO) and Otsuka Long Evans Tokushima Fatty (OLETF) rats were calorie restricted (CR: 50% × 10 days) with or without a 10-day body mass (BM) recovery period, along with their respective

Indexed as

Body WeightCaloric RestrictionInsulin ResistanceAnimalsBlood PressureGluconeogenesisGlucose Tolerance TestKidneyLiverMaleObesityRats, Long-EvansSodium-Glucose Transporter 2Slc5a2 protein, ratSodium-Glucose Transporter 2adipokinescaloric restrictiongluconeogenesisinsulin resistancelipolysis

Identifiers

PMID32587574
PMCPMC7298117
OpenAlexW3035754024

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.