Evidence map›Paper›PMID 32587692›Full record

ArticleSAGE open medicine2020

A prospective community engagement initiative to improve clinical research participation in patients with peripheral artery disease.

Kate Levenberg, David N Proctor, Stephan R Maman, J Carter Luck, Amanda J Miller, Faisal Aziz, John F Radtka, Matthew D Muller

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in SAGE open medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kate LevenbergHeart and Vascular Institute, College of Medicine, Penn State University, Hershey, PA, USA.
David N ProctorHeart and Vascular Institute, College of Medicine, Penn State University, Hershey, PA, USA.
Stephan R MamanHeart and Vascular Institute, College of Medicine, Penn State University, Hershey, PA, USA.
J Carter LuckHeart and Vascular Institute, College of Medicine, Penn State University, Hershey, PA, USA.
Amanda J MillerHeart and Vascular Institute, College of Medicine, Penn State University, Hershey, PA, USA.
Faisal AzizHeart and Vascular Institute, College of Medicine, Penn State University, Hershey, PA, USA.
John F RadtkaHeart and Vascular Institute, College of Medicine, Penn State University, Hershey, PA, USA.
Matthew D MullerHeart and Vascular Institute, College of Medicine, Penn State University, Hershey, PA, USA.ORCID https://orcid.org/0000-0002-7411-8816
Penn State Milton S. Hershey Medical Center · USPennsylvania State University · USUniversity Hospitals of Cleveland · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Penn State Clinical and Translational Science InstituteUL1TR000127 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$17.1M
Penn State Institutional Career Development CoreKL2TR002015 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI VAN SCOY, LAUREN JODI · 2016 to 2025
$7.8M
Penn State Clinical and Translational Science InstituteKL2TR000126 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI SINOWAY, LAWRENCE I · 2012 to 2015
$3.2M
Novel Therapies to Improve Cardiac and Skeletal Muscle O2 Supply-Demand Mismatch in Older Adults with Peripheral Arterial DiseaseR21AG054940 · NIA · PENNSYLVANIA STATE UNIVERSITY, THE · PI PROCTOR, DAVID N · 2018 to 2019
$429k
NCATS NIH HHS KL2 TR000126NCATS NIH HHS KL2 TR002015NCATS NIH HHS UL1 TR000127NCATS NIH HHS UL1 TR002014NIA NIH HHS R21 AG054940
6 · The paper itself

Abstract

objectivePatients diagnosed with peripheral artery disease are difficult to recruit into clinical trials. However, there is currently no high-quality, patient-centered information explaining why peripheral artery disease patients choose to participate or not participate in clinical research studies.

methodsThe current study was a prospective community engagement initiative that specifically asked patients with and without peripheral artery disease: (1) what motivates them to participate in clinical research studies, (2) their willingness to participate in different research procedures, (3) the barriers to participation, (4) preferences about study design, and (5) demographic and disease-related factors influencing participation. Data were gathered through focus groups (

resultsMore than half of the respondents stated that they would be willing to participate in a study during evening or weekend time slots. Peripheral artery disease patients (

conclusionAdults in our geographic region are interested in participating in clinical research studies related to their health; they would like their doctor to tell them what studies they qualify for and they prefer to receive a one-page advertisement that has color pictures of the research procedures. Peripheral artery disease patients are more willing than those without peripheral artery disease to participate in drug infusion studies, trials of investigational drugs, microneurography, and spinal/epidural infusions.

Indexed as

Advertisingagingatherosclerosisbarriers to clinical trial enrollmentcardiovascular healthexercise therapylower extremity blood supply

Identifiers

PMID32587692
PMCPMC7294489
OpenAlexW3035337360

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.