Evidence map›Paper›PMID 32592216›Full record

ArticleAngewandte Chemie (International ed. in English)2020

Alleviating Cellular Oxidative Stress through Treatment with Superoxide-Triggered Persulfide Prodrugs.

Yin Wang, Kearsley M Dillon, Zhao Li, Ethan W Winckler, John B Matson

Open access · greenAbstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 66 citations in OpenAlex.

  1. ROS-responsive HBioactive materials · 2027
    Article
  2. Review
  3. Article
  4. Review
  5. Carbon Dots Derived fromInternational journal of nanomedicine · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Enzyme-Triggered Chemodynamic Therapy via a Peptide-HAngewandte Chemie (International ed. in English) · 2023
    Article
  14. Review
  15. Review
  16. Reactive Sulfur Compounds in the Fight against COVID-19.Antioxidants (Basel, Switzerland) · 2022
    Review
  17. Methods in sulfide and persulfide research.Nitric oxide : biology and chemistry · 2021
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yin WangDepartment of of Chemistry, Virginia Tech Center for Drug Discovery, Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, USA.ORCID 0000-0001-6729-7230
Kearsley M DillonDepartment of of Chemistry, Virginia Tech Center for Drug Discovery, Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, USA.ORCID 0000-0002-0147-8730
Zhao LiDepartment of of Chemistry, Virginia Tech Center for Drug Discovery, Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, USA.ORCID 0000-0002-0457-3020
Ethan W WincklerDepartment of of Chemistry, Virginia Tech Center for Drug Discovery, Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, USA.
John B MatsonDepartment of of Chemistry, Virginia Tech Center for Drug Discovery, Macromolecules Innovation Institute, Virginia Tech, Blacksburg, VA, 24061, USA.ORCID 0000-0001-7984-5396
Virginia Tech · US

Funding

Delivery of H2S: Supramolecular and Enzyme-Triggered Strategies for Controlled ReleaseR01GM123508 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MATSON, JOHN B · 2017 to 2021
$1.6M
NIGMS NIH HHS R01 GM123508
6 · The paper itself

Abstract

Overproduction of superoxide anion (O

Indexed as

AnimalsCell LineHydrogen SulfideMiceMolecular StructureOptical ImagingOxidative StressProdrugsRatsRAW 264.7 CellsSulfidesSuperoxidesHydrogen SulfidepersulfidesProdrugsSulfidesSuperoxidesdrug deliveryoxidative stresspeptidesprodrugsstimuli-responsive

Identifiers

PMID32592216
PMCPMC7719095
OpenAlexW3037452262

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.