Evidence mapPaperPMID 32605987Full record

ArticlemBio2020

Temporal Control of the Helicobacter pylori Cag Type IV Secretion System in a Mongolian Gerbil Model of Gastric Carcinogenesis.

Aung Soe Lin, Mark S McClain, Amber C Beckett, Rhonda R Caston, M Lorena Harvey, Beverly R E A Dixon, Anne M Campbell, Jennifer H B Shuman, Neha Sawhney, Alberto G Delgado and 4 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

  1. Managing dangerous liaisons: lessons fromJournal of bacteriology · 2026
    Review
  2. Article
  3. Infection and immunity · 2025
    Article
  4. A critical review onFrontiers in cellular and infection microbiology · 2025
    Review
  5. Fatty acids ofMicrobiology spectrum · 2024
    Article
  6. Article
  7. Essential role ofInfection and immunity · 2023
    Article
  8. Article
  9. Clinical Pathogenesis, Molecular Mechanisms of Gastric Cancer Development.Current topics in microbiology and immunology · 2023
    Article
  10. Article
  11. Article
  12. Animal Models andJournal of clinical medicine · 2022
    Review
  13. Epigenetics andInternational journal of molecular sciences · 2022
    Review
  14. Enhanced Fitness of a Helicobacter pyloriInfection and immunity · 2021
    Article
  15. TheGut microbes
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Aung Soe Lin *Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Mark S McClain *Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.ORCID 0000-0002-9857-4883
Amber C BeckettDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Rhonda R CastonDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
M Lorena HarveyDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Beverly R E A DixonDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Anne M CampbellDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Jennifer H B ShumanDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Neha SawhneyDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Alberto G DelgadoDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
John T LohDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
M Blanca PiazueloDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Holly M Scott AlgoodDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Timothy L CoverDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA timothy.l.cover@vumc.org.ORCID 0000-0001-8503-002X
Vanderbilt University · US

Funding

Regulation of Helicobacter pylori virulence by dietary factors that impact gastric cancerP01CA116087 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · 2024 to 2025
$5.2M
Translational Analysis CoreP30DK058404 · VANDERBILT UNIVERSITY MEDICAL CENTER · 2002 to 2025
$4.9M
N-NITROSO COMPOUNDS AND GASTRIC CANCERP01CA028842 · VANDERBILT UNIVERSITY · 1985 to 2005
$3.6M
Structure-function analysis of H. pylori VacAR01AI039657 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI TIMOTHY L COVER · 1996 to 2022
$2.5M
Helicobacter pylori and gastrointestinal biologyR01DK058587 · VANDERBILT UNIVERSITY · 2001 to 2005
$1.4M
Type IV Protein Secretion in Helicobacter pyloriR01AI118932 · VANDERBILT UNIVERSITY MEDICAL CENTER · 2025 to 2025
$715k
"Pathogenesis of Helicobacter pylori Infection"I01BX004447 · VETERANS HEALTH ADMINISTRATION · 2025 to 2025
The role of T cell derived cytokines in Helicobacter pyloriI01BX000915 · VA · VETERANS HEALTH ADMINISTRATION · PI HOLLY Marie Scott ALGOOD · 2022 to 2024
BLRD VA I01 BX000915BLRD VA I01 BX004447NCI NIH HHS P01 CA028842NCI NIH HHS P01 CA116087NIAID NIH HHS R01 AI039657NIAID NIH HHS R01 AI118932NIDDK NIH HHS P30 DK058404NIDDK NIH HHS R01 DK058587
6 · The paper itself

Abstract

The

Indexed as

CarcinogenesisAnimalsAntigens, BacterialBacterial ProteinsDisease Models, AnimalDoxycyclineGerbillinaeHelicobacter InfectionsHelicobacter pyloriMaleOperonStomach NeoplasmsType IV Secretion SystemsAntigens, BacterialBacterial ProteinscagA protein, Helicobacter pyloriDoxycyclineType IV Secretion Systemsanimal modelanimal modelscarcinogenesisgastric cancergene regulationHelicobacter pylorihit-and-run hypothesistype IV secretion system

Identifiers

PMID32605987
PMCPMC7327173
OpenAlexW3040539614

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.