ArticleProceedings of the National Academy of Sciences of the United States of America2020
The E3 ubiquitin ligase MARCH1 regulates antimalaria immunity through interferon signaling and T cell activation.
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Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
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Who cites it
29 citing papers in PubMed, 46 citations in OpenAlex.
- Temporal multi-tissue profiling reveals metabolites linked to immune response and malaria parasitemia control.iScience · 2026Article
- Palmitoylation of TBK1 enhances the type I interferon signaling and strengthens anti-malarial immunity in mice.Nature communications · 2025Article
- The E3 ubiquitin ligase MARCH9 alleviates pyroptosis by regulating NLPR3 ubiquitination following myocardial ischemia reperfusion.Cellular and molecular life sciences : CMLS · 2025Article
- Ubiquitination regulates allergic asthma by affecting immune cells and immune responses.Biochemistry and biophysics reports · 2025Review
- Dual nature of type I interferon responses and feedback regulations by SOCS1 dictate malaria mortality.Journal of advanced research · 2025Article
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- Curcumin Inhibits the Growth of Hepatocellular CarcinomaRecent patents on anti-cancer drug discovery · 2025Article
- A Potential Regulatory Network of Selected Human Erythrocytic miRNAs withMicroRNA (Shariqah, United Arab Emirates) · 2025Article
- Malaria: Factors affecting disease severity, immune evasion mechanisms, and reversal of immune inhibition to enhance vaccine efficacy.PLoS pathogens · 2025Review
- Gene Expression and Alternative Splicing Analysis in a Large-Scale Multiple Sclerosis Study.International journal of molecular sciences · 2024Article
- Gene expression and alternative splicing analysis in a large-scale Multiple Sclerosis study.medRxiv : the preprint server for health sciences · 2024Article
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- NAD activates olfactory receptor 1386 to regulate type I interferon responses inProceedings of the National Academy of Sciences of the United States of America · 2024Article
- Exosome‑delivered miR‑486‑3p inhibits the progression of osteosarcoma via sponging CircKEAP1/MARCH1 axis components.Oncology letters · 2024Article
- Article
- Regulation of MHC class II and CD86 expression by March-I in immunity and disease.Current opinion in immunology · 2023Review
- Targeted Protein Degradation for Infectious Diseases: from Basic Biology to Drug Discovery.ACS bio & med chem Au · 2023Review
- Function and regulation of cGAS-STING signaling in infectious diseases.Frontiers in immunology · 2023Review
- Genetic mapping of determinants in drug resistance, virulence, disease susceptibility, and interaction of host-rodent malaria parasites.Parasitology international · 2022Review
- Article
Corrections and comments
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Authors and funding
20 authors at 7 institutions in 2 countries.
Jian WuMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.ORCID 0000-0001-5784-6160
Lu XiaMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.ORCID 0000-0003-2450-1320
Xiangyu YaoMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Xiao YuCenter for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030.
Keyla C TumasMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Wenxiang SunLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Yang ChengLaboratory of Pathogen Infection and Immunity, Department of Public Health and Preventive Medicine, Wuxi School of Medicine, Jiangnan University, Wuxi, 214000 Jiangsu, The People's Republic of China.
Xiao HeMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Yu-Chih PengMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Brajesh K SinghMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.ORCID 0000-0002-2458-5950
Cui ZhangMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Chen-Feng QiPathology Core, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Silvia BollandLaboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Sonja M BestLaboratory of Virology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Channe GowdaDepartment of Biochemistry and Molecular Biology, College of Medicine, Pennsylvania State University, Hershey, PA 17033-0850.ORCID 0000-0002-6860-5108
Ruili HuangNational Center for Advancing Translational Sciences, NIH, Bethesda, MD 20892-8132.
Timothy G MyersGenomic Technologies Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.ORCID 0000-0002-7059-5906
Carole A LongMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132.
Rong-Fu WangCenter for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, TX 77030; xsu@niaid.nih.gov rongfuwa@usc.edu.
Xin-Zhuan SuMalaria Functional Genomics Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD 20892-8132; xsu@niaid.nih.gov rongfuwa@usc.edu.ORCID 0000-0003-3246-3248
National Institute of Allergy and Infectious Diseases · USCentral South University · CNHouston Methodist · USJiangnan University · CNNational Center for Advancing Translational Sciences · USPennsylvania State University · USUniversity of Southern California · US
Funding
Infectious Diseases Research Technologies Core - BethesdaZICAI001051 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2009 to 2025
$226.1MVirus-Host Interactions: Induction and Evasion of Host Innate ImmunityZIAAI001125 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BEST, SONJA · 2010 to 2025
$28.1MGenetic Modifiers Of Autoimmune Disease In FcgammaRIIB Mutant MiceZIAAI000912 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BOLLAND, SILVIA · 2009 to 2025
$27.0MMalaria Parasite Sexual Development, Drug Resistance, and EvolutionZIAAI000892 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI SU, XINZHUAN · 2009 to 2025
$23.3MHost Immune Responses to Antigens of Malaria ParasitesZIAAI001020 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LONG, CAROLE · 2009 to 2025
$13.6MTransport Oncophysics CoreU54CA210181 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI SHEN, HAIFA · 2016 to 2020
$9.3MNovel Strategies for Intervention of Inflammatory Diseases and Cancer - Research Supplement to R01-CA101795R01CA101795 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI WANG, RONGFU · 2004 to 2022
$4.6MToxicology in the 21st Century Program (Tox21) - Computational ToxicologyZIATR000040 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI HUANG, RUILI · 2016 to 2025
$3.5MNCI NIH HHS R01 CA101795NCI NIH HHS U54 CA210181
Abstract
Malaria infection induces complex and diverse immune responses. To elucidate the mechanisms underlying host-parasite interaction, we performed a genetic screen during early (24 h)
Indexed as
AnimalsDisease Models, AnimalFemaleHost-Parasite InteractionsHumansImmunity, InnateInterferon-gammaInterferon Type IInterleukin-10MalariaMaleMiceMice, Inbred C57BLMice, KnockoutPlasmodium yoeliiT-LymphocytesInterferon-gammaInterferon Type IInterleukin-10MARCH1 protein, mouseUbiquitin-Protein Ligaseshost–parasite interactioninnate responseinterferonsPlasmodium
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.