Evidence map›Paper›PMID 32606874›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020

Changes in Body Composition and

Haruhiko Nishida, Katsuko Onishi, Satoshi Kurose, Hiromi Tsutsumi, Takumi Miyauchi, Nana Takao, Sawako Yoshiuchi, Aya Fujii, Yutaka Kimura

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Current Updates on the Understanding of the Role of DNA Methylation on Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  4. Review
  5. FTO and Anthropometrics: The Role of Modifiable Factors.Journal of functional morphology and kinesiology · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Haruhiko NishidaDepartment of Health Science, Kansai Medical University, Osaka, Japan.
Katsuko OnishiDepartment of Health Science, Kansai Medical University, Osaka, Japan.
Satoshi KuroseDepartment of Health Science, Kansai Medical University, Osaka, Japan.
Hiromi TsutsumiDepartment of Health Science, Kansai Medical University, Osaka, Japan.
Takumi MiyauchiHealth Science Center, Kansai Medical University, Osaka, Japan.
Nana TakaoHealth Science Center, Kansai Medical University, Osaka, Japan.
Sawako YoshiuchiHealth Science Center, Kansai Medical University, Osaka, Japan.
Aya FujiiHealth Science Center, Kansai Medical University, Osaka, Japan.
Yutaka KimuraDepartment of Health Science, Kansai Medical University, Osaka, Japan.ORCID 0000-0002-9607-0980
Kansai Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDNA methylation is an epigenetic mechanism that regulates gene expression. The obesity-related ( PARTICIPANTS AND

methodsEighteen female participants (mean age, 50.6 ±12.1 years, body mass index (BMI), 33.5 ± 6.2 kg/m

resultsThe methylation rate was significantly decreased in the NTG in CpG1 (p=0.011) and total value of CpG (p=0.011), whereas in the treatment group containing resistance training (RTG), CpG3 (p=0.038) was increased significantly. Furthermore, the independent factors that determine %CpG3 of RTG were visceral fat area change rate (%VFA) (β = -0.568, P = 0.007, R2 = 0.527) and resistance training (β = 0.517, P = 0.012, R2 = 0.527), which have been extracted.

conclusionA 6-month weight-loss program, including resistance training, may be associated with decreased visceral fat area changes and increased RTG CpG3 methylation changes. However, further replication studies with larger sample sizes are warranted to verify the findings of this study.

Indexed as

body compositionepigeneticsobesityresistance training

Identifiers

PMID32606874
PMCPMC7320880
OpenAlexW3036351553

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.