Evidence map›Paper›PMID 32613416›Full record

SynthesisLasers in medical science2021

The effect of low-level laser therapy as an adjunct to periodontal surgery in the management of postoperative pain and wound healing: a systematic review and meta-analysis.

Han Zhao, Jingchao Hu, Li Zhao

2 registry-linked trialsAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Lasers in medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 4 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05447026 nacompletednot on this map

The Adjunctive Use of Antimicrobial Photodynamic Therapy, Light-emitting-diode Photobiomodulation, and Ozone Therapy in Regenerative Treatment of Stage III Grade C Periodontitis

TypeinterventionalSponsorGazi UniversityRan2018 to 2022Enrolled48ConditionsPeriodontitis, Lasers, Ozone, Wound HealingArmsControl group, Antimicrobial photodynamic therapy (aPDT) group, LED photobiomodulation group, Topical ozone group
NCT06073678 nacompletednot on this mapstarted 2023, after this paper: background citation

Photobiomodulation in Gingival Graft Donor Areas: Clinical, Somatosensory, and Quality of Life Evaluations

TypeinterventionalSponsorUniversity of Sao PauloRan2023 to 2026Enrolled30ConditionsSurgical WoundArmsPhotobiomodulation, Protection with surgical dressing
3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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  7. Wavelength-Dependent Transmitted Irradiance Through Lithium Disilicate Ceramics.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Han ZhaoMulti-disciplinary Treatment Center, Beijing Stomatological Hospital, School of Stomatology, Capital Medical University, Tian Tan Xi Li Number 4, Beijing, 100050, China.ORCID https://orcid.org/0000-0003-0526-610X
Jingchao HuDepartment of Periodontology, Witten/Herdecke University, Alfred-Herrhausen-Str. 45, 58445, Witten, Germany.
Li ZhaoDepartment of Prosthodontics, Stomatological Hospital of Chongqing Medical University, Chongqing, 400015, China. lizhao2010@hospital.cqmu.edu.cn.ORCID https://orcid.org/0000-0001-9308-6808
Witten/Herdecke University · DEStomatological Hospital of Chongqing Medical University · CN

Funding

China Scholarship Council 201809110017
6 · The paper itself

Abstract

The meta-analysis and systematic review aimed to evaluate the effect of low-level laser therapy (LLLT) as an adjunct to periodontal surgery in the management of postoperative pain and wound healing. An electronic search in 4 databases (PubMed, Embase, Cochrane, and OpenGrey) was conducted for randomized clinical trials reporting the effectiveness of LLLT used as an adjunct to periodontal surgery to alleviate pain and accelerate wound healing compared with surgery alone. Finally, 13 studies were eligible and included. The results showed a significant difference of pain relief between groups at day 3 post-surgery, whereas no difference was found at day 7. Moreover, a significant reduction was observed in the mean analgesic intake during the first week in the LLLT group. On day 14, the adjunctive use of LLLT showed significantly faster re-epithelialization and better wound healing in palatal donor sites following free gingival graft procedures. Based on the results, LLLT used as an adjunct to periodontal surgery positively influenced postsurgical pain control. Low power (≤ 500 mW) combined with energy density ≥ 5 J/cm

Indexed as

AnalgesicsCombined Modality TherapyEdemaHumansLow-Level Light TherapyPeriodontiumPostoperative PainPublication BiasRe-EpithelializationRiskTreatment OutcomeWound HealingAnalgesicsLow-level laser therapyPainPeriodontal surgeryRe-epithelializationWound healing

Identifiers

PMID32613416
OpenAlexW3039059309

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.