Evidence map›Paper›PMID 32628045›Full record

ArticleFuture cardiology2021

Diagnostic work-up and therapeutic implications in MINOCA: need for a personalized approach.

Marco Giuseppe Del Buono, Rocco Antonio Montone, Giulia Iannaccone, Maria Chiara Meucci, Riccardo Rinaldi, Domenico D'Amario, Giampaolo Niccoli

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Future cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It reports registered trial NCT05122780. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05122780 phase4unknown status

PROgnostic Value of Precision Medicine in Patients With Myocardial Infarction and Non-obStructive Coronary artEries: the PROMISE Trial.

Ran2021Enrolled120Registered outcomes17Posted comparisons0ConditionsMyocardial Infarction With Non-Obstructive Coronary ArteriesArmsACEi/ARB, Acetylcholine provocative test, Anticoagulant, Antiplatelet Drug, Beta Blocker
PMID 30772224PMID 31709984PMID 31270616PMID 30913893PMID 25587100PMID 30343094PMID 30266608PMID 29954744PMID 29228159PMID 28624816PMID 28476516PMID 28239487other papers from this trial
Open the trial in the graph
3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Guideline on Stress Echocardiography - 2026.Arquivos brasileiros de cardiologia · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Prognostic significance of individual COVADIS criteria in patients undergoing acetylcholine provocation testing.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Precision Medicine in Acute Coronary Syndromes.Journal of clinical medicine · 2024
    Review
  11. Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. ANMCO POSITION PAPER: Prognostic and therapeutic relevance of non-obstructive coronary atherosclerosis.European heart journal supplements : journal of the European Society of Cardiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marco Giuseppe Del BuonoDepartment of Cardiovascular & Thoracic Sciences, Institute of Cardiology, Catholic University of The Sacred Heart, Rome, Italy.
Rocco Antonio MontoneDepartment of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
Giulia IannacconeDepartment of Cardiovascular & Thoracic Sciences, Institute of Cardiology, Catholic University of The Sacred Heart, Rome, Italy.ORCID 0000-0002-7483-7781
Maria Chiara MeucciDepartment of Cardiovascular & Thoracic Sciences, Institute of Cardiology, Catholic University of The Sacred Heart, Rome, Italy.
Riccardo RinaldiDepartment of Cardiovascular & Thoracic Sciences, Institute of Cardiology, Catholic University of The Sacred Heart, Rome, Italy.
Domenico D'AmarioDepartment of Cardiovascular & Thoracic Sciences, Institute of Cardiology, Catholic University of The Sacred Heart, Rome, Italy.
Giampaolo NiccoliDepartment of Cardiovascular & Thoracic Sciences, Institute of Cardiology, Catholic University of The Sacred Heart, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction with non-obstructive coronary artery (MINOCA) disease represents a heterogeneous clinical conundrum accounting for about 6% of all acute myocardial infarction (MI) cases. Initially believed to be a benign condition, is now becoming clear that MINOCA is associated with a non-negligible risk of mortality, rehospitalization, disability and angina burden at follow-up, with high socioeconomic costs. To date, there are no prospective clinical trials in this population and cannot be assumed that benefits observed in patients suffering from MI with obstructive coronary artery disease may successfully translate to this syndrome. Herein, we comment on the importance of the multimodality assessment to properly identify and treat the specific causes of MINOCA, in order to improve prognosis and the quality of life in these patients.

Indexed as

Coronary Artery DiseaseMyocardial InfarctionCoronary AngiographyHumansQuality of LifediagnosisMINOCAprecision medicineTakotsubo syndrometreatmentvasospasm

Identifiers

PMID32628045

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.