Evidence mapPaperPMID 32628427Full record

ArticleJournal of the Chinese Medical Association : JCMA2020

2020 Consensus of Taiwan Society of Cardiology on the pharmacological management of patients with type 2 diabetes and cardiovascular diseases.

Chern-En Chiang, Kwo-Chang Ueng, Ting-Hsing Chao, Tsung-Hsien Lin, Yih-Jer Wu, Kang-Ling Wang, Shih-Hsien Sung, Hung-I Yeh, Yi-Heng Li, Ping-Yen Liu and 17 more

Open access · greenAbstract readConsensus Statement
In one paragraph

Article in Journal of the Chinese Medical Association : JCMA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Review
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  4. Article
  5. Article
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  8. Review
  9. Association between glycated hemoglobin and ambulatory blood pressure or heart rate in hypertensive patients.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 13 institutions in 1 country.

Chern-En ChiangGeneral Clinical Research Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Kwo-Chang UengChung-Shan Medical University Hospital, Taichung, Taiwan, ROC.
Ting-Hsing ChaoDepartment of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.
Tsung-Hsien LinDepartment of Internal Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Yih-Jer WuDepartment of Medicine, Mackay Medical College, New Taipei City, Taiwan, ROC.
Kang-Ling WangGeneral Clinical Research Center, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Shih-Hsien SungDepartment of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Hung-I YehDepartment of Medicine, Mackay Medical College, New Taipei City, Taiwan, ROC.
Yi-Heng LiDivision of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.
Ping-Yen LiuDivision of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC.
Kuan-Cheng ChangDivision of Cardiovascular Medicine, China Medical University Hospital, Taichung, Taiwan, ROC.
Kou-Gi ShyuDivision of Cardiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan, ROC.
Jin-Long HuangCardiovascular center, Taichung Veterans General Hospital, Taichung, Taiwan, ROC.
Cheng-Dao TsaiDepartment of Medicine, Changhua Christian Hospital, Changhua, Taiwan, ROC.
Huei-Fong HungDivision of Cardiology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan, ROC.
Ming-En LiuDivision of Cardiology, Department of Internal Medicine, Hsinchu Mackay Memorial Hospital, Hsinchu, Taiwan, ROC.
Tze-Fan ChaoDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Shu-Meng ChengDivision of Cardiology, Department of Medicine, Tri-Service General Hospital, Taipei, Taiwan, ROC.
Hao-Min ChengDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Pao-Hsien ChuDepartment of Cardiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.
Wei-Hsian YinSchool of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Yen-Wen WuSchool of Medicine, National Yang-Ming University, Taipei, Taiwan, ROC.
Wen-Jone ChenDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC.
Wen-Ter LaiDepartment of Internal Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, ROC.
Shing-Jong LinTaipei Heart Institute, Taipei Medical University, Taipei, Taiwan, ROC.
San-Jou YehDepartment of Cardiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.
Juey-Jen HwangCardiovascular Division, Department of Internal Medicine, National Taiwan, ROC, University College of Medicine and Hospital, Taipei, Taiwan, ROC.
Chang Gung Memorial Hospital · TWNational Cheng Kung University Hospital · TWNational Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TWKaohsiung Medical University · TWMackay Memorial Hospital · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TWChanghua Christian Hospital · TWChina Medical University · TWChung Shan Medical University Hospital · TWFar Eastern Memorial Hospital · TWTaichung Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global incidence and prevalence of type 2 diabetes have been escalating in recent decades. The total diabetic population is expected to increase from 415 million in 2015 to 642 million by 2040. Patients with type 2 diabetes have an increased risk of atherosclerotic cardiovascular disease (ASCVD). About two-thirds of patients with type 2 diabetes died of ASCVD. The association between hyperglycemia and elevated cardiovascular (CV) risk has been demonstrated in multiple cohort studies. However, clinical trials of intensive glucose reduction by conventional antidiabetic agents did not significantly reduce macrovascular outcomes.In December 2008, U.S. Food and Drug Administration issued a mandate that every new antidiabetic agent requires rigorous assessments of its CV safety. Thereafter, more than 200,000 patients have been enrolled in a number of randomized controlled trials (RCTs). These trials were initially designed to prove noninferiority. It turned out that some of these trials demonstrated superiority of some new antidiabetic agents versus placebo in reducing CV endpoints, including macrovascular events, renal events, and heart failure. These results are important in clinical practice and also provide an opportunity for academic society to formulate treatment guidelines or consensus to provide specific recommendations for glucose control in various CV diseases.In 2018, the Taiwan Society of Cardiology (TSOC) and the Diabetes Association of Republic of China (DAROC) published the first joint consensus on the "Pharmacological Management of Patients with Type 2 Diabetes and Cardiovascular Diseases." In 2020, TSOC appointed a new consensus group to revise the previous version. The updated 2020 consensus was comprised of 5 major parts: (1) treatment of diabetes in patients with multiple risk factors, (2) treatment of diabetes in patients with coronary heart disease, (3) treatment of diabetes in patients with stage 3 chronic kidney disease, (4) treatment of diabetes in patients with a history of stroke, and (5) treatment of diabetes in patients with heart failure. The members of the consensus group thoroughly reviewed all the evidence, mainly RCTs, and also included meta-analyses and real-world evidence. The treatment targets of HbA1c were finalized. The antidiabetic agents were ranked according to their clinical evidence. The consensus is not mandatory. The final decision may need to be individualized and based on clinicians' discretion.

Indexed as

CardiologyCardiovascular DiseasesDiabetes Mellitus, Type 2Diabetic AngiopathiesDiabetic NephropathiesHeart FailureHumansHypoglycemic AgentsMetforminSocieties, MedicalTaiwanHypoglycemic AgentsMetformin

Identifiers

PMID32628427
PMCPMC12999102
OpenAlexW3034908645

What Socratic holds

Texttitle and abstract
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.