Evidence map›Paper›PMID 32628937›Full record

ArticleDevelopmental biology2020

Ets1 functions partially redundantly with Etv2 to promote embryonic vasculogenesis and angiogenesis in zebrafish.

Satish Casie Chetty, Saulius Sumanas

Open access · greenAbstract read
In one paragraph

Article in Developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Tiliroside fromInternational journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Satish Casie ChettyDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA; Molecular and Developmental Biology Graduate Program, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA.
Saulius SumanasDivision of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 45229, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA. Electronic address: saulius.sumanas@cchmc.org.
Cincinnati Children's Hospital Medical Center · US

Funding

Molecular Mechanisms of Arterial-Venous Differentiation in ZebrafishR01HL107369 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI SUMANAS, SAULIUS · 2011 to 2015
$1.9M
Characterization of a novel hematopoietic siteR21AI128445 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI SUMANAS, SAULIUS · 2017 to 2018
$429k
NHLBI NIH HHS R01 HL107369NIAID NIH HHS R21 AI128445
6 · The paper itself

Abstract

ETS transcription factors play an important role in the specification and differentiation of endothelial cells during vascular development. Despite previous studies, the role of the founding member of the ETS family, Ets1, in vascular development in vivo is only partially understood. Here, we generated a zebrafish ets1 mutant by TALEN genome editing and tested functional redundancy between Ets1 and a related ETS factor Etv2/Etsrp/ER71. While zebrafish ets1

Indexed as

Neovascularization, PhysiologicAnimalsApoptosisEmbryo, NonmammalianGene Knockout TechniquesMAP Kinase Kinase 1Proto-Oncogene Protein c-ets-1Vascular Endothelial Growth Factor Receptor-2ZebrafishZebrafish ProteinsEtv2 protein, zebrafishMAP2K1 protein, zebrafishMAP Kinase Kinase 1Proto-Oncogene Protein c-ets-1Vascular Endothelial Growth Factor Receptor-2Zebrafish ProteinsAngiogenesisETS transcription FactorsVascular developmentVasculogenesisZebrafish

Identifiers

PMID32628937
PMCPMC7484174
OpenAlexW3038602833

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.