Evidence mapPaperPMID 32629979Full record

ArticleInternational journal of molecular sciences2020

Food for Bone: Evidence for a Role for Delta-Tocotrienol in the Physiological Control of Osteoblast Migration.

Lavinia Casati, Francesca Pagani, Roberto Maggi, Francesco Ferrucci, Valeria Sibilia

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Role of vitamins beyond vitamin DInternational journal of molecular medicine · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Revisiting the therapeutic potential of tocotrienol.BioFactors (Oxford, England) · 2022
    Review
  9. Sex Steroid Regulation of Oxidative Stress in Bone Cells: An In Vitro Study.International journal of environmental research and public health · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lavinia CasatiDepartment of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, 20129 Milano, Italy.ORCID 0000-0001-9044-6767
Francesca PaganiDepartment of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, 20129 Milano, Italy.
Roberto MaggiDepartment of Pharmaceutical Sciences, Università degli Studi di Milano, 20133 Milano, Italy.
Francesco FerrucciDepartment of Health, Animal Science and Food Safety, Università degli Studi di Milano, 20133 Milano, Italy.
Valeria SibiliaDepartment of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, 20129 Milano, Italy.ORCID 0000-0003-1250-724X
University of Milan · IT

Funding

Fondazione Cariplo 0834/2015
6 · The paper itself

Abstract

Bone remodeling and repair require osteogenic cells to reach the sites that need to be rebuilt, indicating that stimulation of osteoblast migration could be a promising osteoanabolic strategy. We showed that purified δ-tocotrienol (δ-TT, 10 μg/mL), isolated from commercial palm oil (

Indexed as

Animalsbeta CateninCell CycleCell LineCell MovementDrug Evaluation, PreclinicalHistone AcetyltransferasesMiceOsteoblastsTranscriptional ActivationVitamin Ebeta CateninHistone Acetyltransferasestocotrienol, deltaVitamin Edelta-tocotrienolH3 and H4 acetylation levelMC3T3-E1 cellsosteoblast migrationWnt/β-catenin pathway

Identifiers

PMID32629979
PMCPMC7370057
OpenAlexW3039116331

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.