Evidence map›Paper›PMID 32630706›Full record

ReviewAntioxidants (Basel, Switzerland)2020

Reactive Species in Huntington Disease: Are They Really the Radicals You Want to Catch?

José Bono-Yagüe, Ana Pilar Gómez-Escribano, José María Millán, Rafael Pascual Vázquez-Manrique

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 46 citations in OpenAlex.

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  16. The flavonoid luteolin reduces mutant huntingtin aggregation and cytotoxicity in huntingtin-mutated neuroblastoma cells.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

José Bono-YagüeLaboratory of Molecular, Cellular and Genomic Biomedicine, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.ORCID 0000-0001-9651-1099
Ana Pilar Gómez-EscribanoLaboratory of Molecular, Cellular and Genomic Biomedicine, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.
José María MillánLaboratory of Molecular, Cellular and Genomic Biomedicine, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.ORCID 0000-0002-7211-9129
Rafael Pascual Vázquez-ManriqueLaboratory of Molecular, Cellular and Genomic Biomedicine, Instituto de Investigación Sanitaria La Fe, 46026 Valencia, Spain.ORCID 0000-0002-1594-0033
Centre for Biomedical Network Research on Rare Diseases · ESInstituto de Investigación Sanitaria La Fe · ES

Funding

Conselleria d'Educació, Investigació, Cultura i Esport ACIF/2019/249Fundació Marató de TV3 559Fundación Ramón Areces CIVP19S8119Instituto de Salud Carlos III CIBERER-ACCI2019Instituto de Salud Carlos III CPII16/00004Instituto de Salud Carlos III PI14/00949Instituto de Salud Carlos III PI17/00011VII Convocatoria Ayudas a la Investigación MHER Ayuda Miguel Gil award
6 · The paper itself

Abstract

Huntington disease (HD) is a neurodegenerative condition and one of the so-called rare or minority diseases, due to its low prevalence (affecting 1-10 of every 100,000 people in western countries). The causative gene,

Indexed as

antioxidantsastrocytesC. elegansclinical trialsDrosophilafree radicalshuntingtinHuntington diseaseinflammationmicrogliamouse modelsneurodegenerationoxidative stress

Identifiers

PMID32630706
PMCPMC7401865
OpenAlexW3039607033

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.