Evidence map›Paper›PMID 32633463›Full record

ArticleJournal of cellular and molecular medicine2020

Hydrogen sulphide ameliorating skeletal muscle atrophy in db/db mice via Muscle RING finger 1 S-sulfhydration.

Fangping Lu, Baoling Lu, Linxue Zhang, JingChen Wen, Mengyi Wang, Shiwu Zhang, Qianzhu Li, Feng Shu, Yu Sun, Ning Liu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. HHandbook of experimental pharmacology · 2026
    Review
  3. CSE/HJournal of cachexia, sarcopenia and muscle · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. HFrontiers in physiology · 2022
    Article
  15. The Impact of HAntioxidants (Basel, Switzerland) · 2021
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Fangping LuDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Baoling LuDepartment of Infectious, The Fourth Hospital of Harbin Medical University, Harbin, China.
Linxue ZhangDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
JingChen WenDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Mengyi WangDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Shiwu ZhangDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Qianzhu LiDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Feng ShuDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Yu SunDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Ning LiuDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Shuo PengDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Yajun ZhaoDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Shiyun DongDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Dechao ZhaoDepartment of Cardiology, First Affiliated Hospital of Harbin Medical University, Harbin, China.
Fanghao LuDepartment of Pathophysiology, Harbin Medical University, Harbin, China.
Weihua ZhangDepartment of Pathophysiology, Harbin Medical University, Harbin, China.ORCID 0000-0002-4165-5260
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Muscle atrophy occurs in many pathological states, including cancer, diabetes and sepsis, whose results primarily from accelerated protein degradation and activation of the ubiquitin-proteasome pathway. Expression of Muscle RING finger 1 (MuRF1), an E3 ubiquitin ligase, was increased to induce the loss of muscle mass in diabetic condition. However, hydrogen sulphide (H

Indexed as

AnimalsDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2GasotransmittersGene Expression RegulationHydrogen SulfideMiceMice, Inbred C57BLMice, Inbred StrainsMuscle ProteinsMuscle, SkeletalMuscular AtrophyProteolysisTripartite Motif ProteinsUbiquitinationUbiquitin-Protein LigasesGasotransmittersHydrogen SulfideMuscle ProteinsTrim63 protein, mouseTripartite Motif ProteinsUbiquitin-Protein Ligasesdiabetes mellitushydrogen sulphideMuscle RING finger 1skeletal muscle atrophyS-sulfhydration modification

Identifiers

PMID32633463
PMCPMC7417732
OpenAlexW3040979944

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.