Evidence map›Paper›PMID 32636234›Full record

ArticleMolecular & cellular proteomics : MCP2020

Examining and Fine-tuning the Selection of Glycan Compositions with GlyConnect Compozitor.

Thibault Robin, Julien Mariethoz, Frédérique Lisacek

Abstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Role of B Cell and T Cell Glycosylation in Systemic Lupus Erythematosus.International journal of molecular sciences · 2023
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Bioinformatics in Immunoglobulin Glycosylation Analysis.Experientia supplementum (2012) · 2021
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thibault RobinProteome Informatics Group, SIB Swiss Institute of Bioinformatics, CMU, Geneva, Switzerland; Computer Science Dept., Faculty of Science, University of Geneva, Switzerland; CALIPHO Group, SIB Swiss Institute of BioinformaticsCMU, Geneva, Switzerland; Microbiology and Molecular Medicine Dept., Faculty of Medicine, University of Geneva, Switzerland.
Julien MariethozProteome Informatics Group, SIB Swiss Institute of Bioinformatics, CMU, Geneva, Switzerland; Computer Science Dept., Faculty of Science, University of Geneva, Switzerland.
Frédérique LisacekProteome Informatics Group, SIB Swiss Institute of Bioinformatics, CMU, Geneva, Switzerland; Computer Science Dept., Faculty of Science, University of Geneva, Switzerland; Section of Biology, Faculty of Science, University of Geneva, Switzerland. Electronic address: frederique.lisacek@sib.swiss.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A key point in achieving accurate intact glycopeptide identification is the definition of the glycan composition file that is used to match experimental with theoretical masses by a glycoproteomics search engine. At present, these files are mainly built from searching the literature and/or querying data sources focused on posttranslational modifications. Most glycoproteomics search engines include a default composition file that is readily used when processing MS data. We introduce here a glycan composition visualizing and comparative tool associated with the GlyConnect database and called GlyConnect Compozitor. It offers a web interface through which the database can be queried to bring out contextual information relative to a set of glycan compositions. The tool takes advantage of compositions being related to one another through shared monosaccharide counts and outputs interactive graphs summarizing information searched in the database. These results provide a guide for selecting or deselecting compositions in a file in order to reflect the context of a study as closely as possible. They also confirm the consistency of a set of compositions based on the content of the GlyConnect database. As part of the tool collection of the Glycomics@ExPASy initiative, Compozitor is hosted at https://glyconnect.expasy.org/compozitor/ where it can be run as a web application. It is also directly accessible from the GlyConnect database.

Indexed as

GlycomicsAnimalsCHO CellsCricetulusDatabases, FactualHumansImmunoglobulin GIntegrinsMucinsPolysaccharidesImmunoglobulin GIntegrinsMucinsPolysaccharidesbioinformatics softwaredata evaluationglycomicsGlycoproteinsglycoproteomics

Identifiers

PMID32636234
PMCPMC8014996

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.