Evidence map›Paper›PMID 32640539›Full record

ArticleMolecules (Basel, Switzerland)2020

Otoprotective Effect of 2,3,4',5-Tetrahydroxystilbene-2-

Yu-Hsuan Wen, Jia-Ni Lin, Rong-Shuan Wu, Szu-Hui Yu, Chuan-Jen Hsu, Guo-Fang Tseng, Hung-Pin Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yu-Hsuan WenInstitute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan.
Jia-Ni LinDepartment of Otolaryngology, Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427213, Taiwan.
Rong-Shuan WuThe Affiliated Senior High School of National Chung Hsing University, Taichung 412011, Taiwan.
Szu-Hui YuDepartment of Music, Tainan University of Technology, Tainan 710302, Taiwan.
Chuan-Jen HsuDepartment of Otolaryngology, Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427213, Taiwan.ORCID 0000-0002-7548-7736
Guo-Fang TsengInstitute of Medical Sciences, Tzu Chi University, Hualien 970374, Taiwan.
Hung-Pin WuDepartment of Otolaryngology, Head and Neck Surgery, Taichung Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Taichung 427213, Taiwan.ORCID 0000-0003-3336-6319
Tzu Chi University · TWNational Chung Hsing University · TWNational Taiwan University Hospital · TWTainan University of Technology · TW

Funding

Buddhist Tzu Chi Medical Foundation TCMF-MP 108-01-01
6 · The paper itself

Abstract

Excessive levels of reactive oxygen species (ROS) lead to mitochondrial damage and apoptotic cell death in gentamicin-induced ototoxicity. 2,3,4',5-Tetrahydroxystilbene-2-

Indexed as

AnimalsApoptosisApoptosis Regulatory ProteinsCell LineCell SurvivalFallopia multifloraGentamicinsGlucosidesL-Lactate DehydrogenaseMembrane Potential, MitochondrialMiceMitochondriaOtotoxicityReactive Oxygen SpeciesStilbenesSuperoxide Dismutase2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranosideApoptosis Regulatory ProteinsGentamicinsGlucosidesL-Lactate DehydrogenaseReactive Oxygen SpeciesStilbenesSuperoxide Dismutase2,3,4′,5-tetrahydroxystilbene-2-O-β-d-glucoside (THSG)gentamicinotoprotectionPolygonum multiflorum Thunb.reactive oxygen species (ROS)UB/OC-2 cells

Identifiers

PMID32640539
PMCPMC7412181
OpenAlexW3040111787

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.