Evidence map›Paper›PMID 32640721›Full record

ReviewBioengineering (Basel, Switzerland)2020

Prospects and Challenges of Translational Corneal Bioprinting.

Matthias Fuest, Gary Hin-Fai Yam, Jodhbir S Mehta, Daniela F Duarte Campos

Open access · goldAbstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
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  11. Article
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  13. Article
  14. Cell-Biomaterial Interactions.Bioengineering (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Three-dimensional bioprinting in ophthalmic care.International journal of ophthalmology · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Matthias FuestDepartment of Ophthalmology, RWTH Aachen University, 52074 Aachen, Germany.
Gary Hin-Fai YamDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Jodhbir S MehtaTissue Engineering and Stem Cell Group, Singapore Eye Research Institute, Singapore 169856, Singapore.
Daniela F Duarte CamposInstitute of Applied Medical Engineering, RWTH Aachen University, 52074 Aachen, Germany.
DWI – Leibniz Institute for Interactive Materials · DERWTH Aachen University · DESingapore National Eye Center · SGUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corneal transplantation remains the ultimate treatment option for advanced stromal and endothelial disorders. Corneal tissue engineering has gained increasing interest in recent years, as it can bypass many complications of conventional corneal transplantation. The human cornea is an ideal organ for tissue engineering, as it is avascular and immune-privileged. Mimicking the complex mechanical properties, the surface curvature, and stromal cytoarchitecure of the in vivo corneal tissue remains a great challenge for tissue engineering approaches. For this reason, automated biofabrication strategies, such as bioprinting, may offer additional spatial control during the manufacturing process to generate full-thickness cell-laden 3D corneal constructs. In this review, we discuss recent advances in bioprinting and biomaterials used for in vitro and ex vivo corneal tissue engineering, corneal cell-biomaterial interactions after bioprinting, and future directions of corneal bioprinting aiming at engineering a full-thickness human cornea in the lab.

Indexed as

3Dbioprintingcell-biomaterial interactioncorneal tissue engineeringhydrogel

Identifiers

PMID32640721
PMCPMC7552635
OpenAlexW3039483480

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.