Evidence map›Paper›PMID 32647173›Full record

ReviewNature reviews. Disease primers2020

Autoimmune gastritis.

Marco Vincenzo Lenti, Massimo Rugge, Edith Lahner, Emanuela Miceli, Ban-Hock Toh, Robert M Genta, Christophe De Block, Chaim Hershko, Antonio Di Sabatino

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Disease primers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 167 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed, 9 pooled it
29.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06272500 narecruitingnot on this mapstarted 2024, after this paper: background citation

Safety and Efficacy Study of Betaine Hydrochloride in Treating Hypergastrinemia in Patients With Autoimmune Gastritis.

TypeinterventionalSponsorJianning YaoRan2024 to 2026Enrolled60ConditionsAutoimmune GastritisArmsoral administration of receives only oral administration of placebo, oral administration of Betaine hydrochloride
NCT06881511 narecruitingnot on this mapstarted 2025, after this paper: background citation

Exploratory Study on the Efficacy of Betaine Hydrochloride in Treating Autoimmune Gastritis

TypeinterventionalSponsorSecond Affiliated Hospital, Zhejiang University, School of MedicineRan2025 to 2026Enrolled100ConditionsAutoimmune GastritisArmsNo intervention (Control Group), Oral betaine hydrochloride (2 capsules, 3 times daily)
3 · Its place in the literature

Who cites it

167 citing papers in PubMed, 9 syntheses or guidelines pooled it, 311 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Guideline
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Guideline
  10. Journal of translational autoimmunity · 2026
    Article
  11. Article
  12. Observational
  13. Gastric Mucosa Cancer Risk: The Operative Link on Gastritis Assessment Staging System.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Review
  14. The Evolution of Autoimmune Gastritis Research (1995-2025): A Hybrid Bibliometric-Conceptual Synthesis.The Korean journal of helicobacter and upper gastrointestinal research · 2026
    Article
  15. Article
  16. Autoimmune gastritis: emerging insights and clinical management.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  17. Eosinophilic gastrointestinal diseases.Nature reviews. Disease primers · 2026
    Review
  18. Review
  19. Article
  20. Article

107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 5 countries.

Marco Vincenzo LentiDepartment of Internal Medicine, IRCCS San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Massimo RuggeDepartment of Medicine (DIMED), Surgical Pathology & Cytopathology Unit, University of Padua, Padua, Italy.
Edith LahnerDepartment of Surgical-Medical Sciences and Translational Medicine, Digestive and Liver Disease Unit, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Emanuela MiceliDepartment of Internal Medicine, IRCCS San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Ban-Hock TohCentre for Inflammatory Diseases, Monash Health, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.
Robert M GentaDepartment of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, Texas, USA.
Christophe De BlockDepartment of Endocrinology, Diabetology and Metabolism, Faculty of Medicine, Antwerp University Hospital and University of Antwerp, Antwerpen, Belgium.
Chaim HershkoDepartment of Hematology, Shaare Zedek Medical Center, Hebrew University of Jerusalem, Jerusalem, Israel.
Antonio Di SabatinoDepartment of Internal Medicine, IRCCS San Matteo Hospital Foundation, University of Pavia, Pavia, Italy. a.disabatino@smatteo.pv.it.
University of Pavia · ITBaylor College of Medicine · USHebrew University of Jerusalem · ILMonash University · AUSapienza University of Rome · ITUniversity of Antwerp · BEUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune gastritis (AIG) is an increasingly prevalent, organ-specific, immune-mediated disorder characterized by the destruction of gastric parietal cells, leading to the loss of intrinsic factor and reduced acid output. These alterations result in malabsorption of iron, vitamin B

Indexed as

Disease ManagementGraves DiseaseHumansReceptors, ThyrotropinReceptors, ThyrotropinTSHR protein, human

Identifiers

PMID32647173
OpenAlexW4211023055

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.