Evidence map›Paper›PMID 32649059›Full record

ArticleJournal of biophotonics2020

A deep-learning-based approach for noise reduction in high-speed optical coherence Doppler tomography.

Ang Li, Congwu Du, Nora D Volkow, Yingtian Pan

Abstract read
In one paragraph

Article in Journal of biophotonics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ang LiDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, New York, USA.ORCID 0000-0003-4252-9933
Congwu DuDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, New York, USA.
Nora D VolkowNational Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland, USA.
Yingtian PanDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, New York, USA.

Funding

Neurobiology of Substance Abuse and AddictionZIAAA000550 · NIAAA · NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM · PI VOLKOW, NORA D. · 2009 to 2025
$115.1M
Calcium-related Neurotoxicity of CocaineR01DA029718 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI DU, CONGWU, PAN, YINGTIAN · 2012 to 2025
$4.2M
Neuro-glio-vascular interactions in vivo probed with optical imagingRF1DA048808 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI DU, CONGWU, PAN, YINGTIAN · 2019 to 2019
$1.2M
Optical platform to image neuronal and vascular effects of cocaine in awake rodentsR21DA042597 · NIDA · STATE UNIVERSITY NEW YORK STONY BROOK · PI DU, CONGWU, PAN, YINGTIAN · 2016 to 2017
$392k
NIDA NIH HHS R01 DA029718NIDA NIH HHS R21 DA042597NIDA NIH HHS RF1 DA048808NIH HHS R01DA029718NIH HHS R21DA042597NIH HHS RF1DA048808
6 · The paper itself

Abstract

Optical coherence Doppler tomography (ODT) increasingly attracts attention because of its unprecedented advantages with respect to high contrast, capillary-level resolution and flow speed quantification. However, the trade-off between the signal-to-noise ratio of ODT images and A-scan sampling density significantly slows down the imaging speed, constraining its clinical applications. To accelerate ODT imaging, a deep-learning-based approach is proposed to suppress the overwhelming phase noise from low-sampling density. To handle the issue of limited paired training datasets, a generative adversarial network is performed to implicitly learn the distribution underlying Doppler phase noise and to generate the synthetic data. Then a 3D based convolutional neural network is trained and applied for the image denoising. We demonstrate this approach outperforms traditional denoise methods in noise reduction and image details preservation, enabling high speed ODT imaging with low A-scan sampling density.

Indexed as

Tomography, Optical CoherenceDeep LearningImage Processing, Computer-AssistedNeural Networks, ComputerSignal-To-Noise Ratiocerebral capillary flow imagingdeep learningimaging speed improvementoptical coherence Doppler tomography

Identifiers

PMID32649059
PMCPMC7722172

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.