Evidence map›Paper›PMID 32650394›Full record

ArticleMarine drugs2020

Bioactive Polyphenols from Southern Chile Seaweed as Inhibitors of Enzymes for Starch Digestion.

Luz Verónica Pacheco, Javier Parada, José Ricardo Pérez-Correa, María Salomé Mariotti-Celis, Fernanda Erpel, Angara Zambrano, Mauricio Palacios

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Review
  3. Valorization of Brown Seaweed (Foods (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Sustainable Recovery of Phlorotannins fromAntioxidants (Basel, Switzerland) · 2025
    Article
  7. Foods (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Article
  10. The Ocean's Pharmacy: Health Discoveries in Marine Algae.Molecules (Basel, Switzerland) · 2024
    Review
  11. The Potential of Using Cochayuyo (Foods (Basel, Switzerland) · 2024
    Article
  12. Review
  13. Review
  14. Cochayuyo (Foods (Basel, Switzerland) · 2023
    Article
  15. International journal of molecular sciences · 2023
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Pressurized Hot Liquid Extraction with 15%Antioxidants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Luz Verónica PachecoGraduate School, Faculty of Agricultural Sciences, Universidad Austral de Chile, Valdivia 5090000, Chile.
Javier ParadaInstitute of Food Science and Technology, Faculty of Agricultural Sciences, Universidad Austral de Chile, Valdivia 5090000, Chile.ORCID 0000-0001-9085-1770
José Ricardo Pérez-CorreaDepartment of Chemical and Bioprocess Engineering, Pontificia Universidad Católica de Chile, Macul, Santiago 7810000, Chile.ORCID 0000-0002-1278-7782
María Salomé Mariotti-CelisPrograma Institucional de Fomento a la Investigación, Desarrollo e Innovación, Universidad Tecnológica Metropolitana, Santiago 8940577, Chile.
Fernanda ErpelDepartment of Chemical and Bioprocess Engineering, Pontificia Universidad Católica de Chile, Macul, Santiago 7810000, Chile.
Angara ZambranoInstituto de Bioquímica y Microbiología, Facultad de Ciencias, Universidad Austral de Chile, Valdivia 5090000, Chile.ORCID 0000-0001-9359-2786
Mauricio PalaciosCentro FONDAP de Investigación Dinámica de Ecosistemas Marinos de Altas Latitudes (IDEAL), Valdivia 5090000, Chile.ORCID 0000-0002-5484-8459
Austral University of Chile · CLPontificia Universidad Católica de Chile · CLMetropolitan University of Technology · CL

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 1170594
6 · The paper itself

Abstract

The increment of non-communicable chronic diseases is a constant concern worldwide, with type-2 diabetes mellitus being one of the most common illnesses. A mechanism to avoid diabetes-related hyperglycemia is to reduce food digestion/absorption by using anti-enzymatic (functional) ingredients. This research explored the potential of six common Chilean seaweeds to obtain anti-hyperglycemic polyphenol extracts, based on their capacity to inhibit key enzymes related with starch digestion. Ethanol/water hot pressurized liquid extraction (HPLE), which is an environmentally friendly method, was studied and compared to conventional extraction with acetone. Total polyphenols (TP), antioxidant activity, cytotoxicity and inhibition capacity on α-glucosidase and α-amylase were analyzed. Results showed that the

Indexed as

SeaweedChileDiabetes Mellitus, Type 2DigestionGlycoside Hydrolase InhibitorsHumansHyperglycemiaOceans and SeasPolyphenolsStarchGlycoside Hydrolase InhibitorsPolyphenolsStarchcochayuyoenzyme inhibitionhypoglycemic effectseaweed polyphenolsstarch digestion

Identifiers

PMID32650394
PMCPMC7401274
OpenAlexW3041459902

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.