Evidence map›Paper›PMID 32650488›Full record

ArticleBiomolecules2020

Molecular Insights of Copper Sulfate Exposure-Induced Nephrotoxicity: Involvement of Oxidative and Endoplasmic Reticulum Stress Pathways.

Chongshan Dai, Qiangqiang Liu, Daowen Li, Gaurav Sharma, Jianli Xiong, Xilong Xiao

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Chongshan DaiCollege of Veterinary Medicine, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China.ORCID 0000-0002-4677-0524
Qiangqiang LiuCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471023, China.
Daowen LiCollege of Veterinary Medicine, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China.
Gaurav SharmaAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID 0000-0002-1754-7163
Jianli XiongCollege of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471023, China.
Xilong XiaoCollege of Veterinary Medicine, China Agricultural University, No. 2 Yuanmingyuan West Road, Beijing 100193, China.
Henan University of Science and Technology · CNChina Agricultural University · CNSouthwestern Medical Center · US

Funding

Key Projects in Chinese National Science and Technology Pillar Program during the 12th Five-year Plan Period 2015BAD11B03
6 · The paper itself

Abstract

The precise pathogenic mechanism in Cu exposure-cause nephrotoxicity remains unclear. This study investigated the underlying molecular mechanism of copper sulfate (CuSO

Indexed as

AnimalsCaspase 12Caspase 3Caspase 9Copper SulfateDisease Models, AnimalEndoplasmic Reticulum Chaperone BiPEndoplasmic Reticulum StressGene Expression RegulationHeat-Shock ProteinsHEK293 CellsHumansKidney DiseasesMaleMembrane GlycoproteinsMice4-phenylbutyric acidCasp12 protein, mouseCasp3 protein, mouseCasp9 protein, mouseCaspase 12Caspase 3Caspase 9Copper SulfateDdit3 protein, mouseEndoplasmic Reticulum Chaperone BiPendoplasminHeat-Shock ProteinsHSPA5 protein, humanHspa5 protein, mouseMembrane GlycoproteinsPhenylbutyratesTranscription Factor CHOPapoptosiscoppercytotoxicityendoplasmic reticulum stresskidneyoxidative stress

Identifiers

PMID32650488
PMCPMC7407214
OpenAlexW3040795482

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.