Evidence map›Paper›PMID 32665269›Full record

ArticlemBio2020

SERINC5 Potently Restricts Retrovirus Infection

Uddhav Timilsina, Supawadee Umthong, Brian Lynch, Aimee Stablewski, Spyridon Stavrou

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. SERINC4 is dispensable for male fertility and spermatogenesis in mice.American journal of translational research · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. SERINC5 counters retroviruses and non-retroviruses.Frontiers in cellular and infection microbiology · 2024
    Review
  9. Review
  10. HIV-1 restriction by SERINC5.Medical microbiology and immunology · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Uddhav TimilsinaDepartment of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.
Supawadee UmthongDepartment of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.
Brian LynchDepartment of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA.
Aimee StablewskiDepartment of Molecular and Cell Biology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Spyridon StavrouDepartment of Microbiology and Immunology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, USA stavrou2@buffalo.edu.ORCID 0000-0002-3962-8917
University at Buffalo, State University of New York · USRoswell Park Comprehensive Cancer Center · US

Funding

The role of SERINC5 during retrovirus infection in vivoR21AI144147 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI STAVROU, SPYRIDON · 2020 to 2021
$436k
NIAID NIH HHS R21 AI144147
6 · The paper itself

Abstract

The

Indexed as

Host-Pathogen InteractionsAnimalsFemaleGlycosylationLeukemia, ExperimentalLeukemia Virus, MurineMaleMembrane GlycoproteinsMembrane ProteinsMiceMice, Inbred C57BLMice, KnockoutNerve Tissue ProteinsRetroviridae InfectionsTumor Virus InfectionsMembrane GlycoproteinsMembrane ProteinsNerve Tissue ProteinsSerinc3 protein, mouseSerinc5 protein, mouseantiretroviral responseglycosylated gagin vivo modelSERINC3SERINC5

Identifiers

PMID32665269
PMCPMC7360926
OpenAlexW3043040355

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.