Evidence map›Paper›PMID 32669468›Full record

ArticlemSphere2020

Transforming Properties of Beta-3 Human Papillomavirus E6 and E7 Proteins.

Lucia Minoni, Maria Carmen Romero-Medina, Assunta Venuti, Cécilia Sirand, Alexis Robitaille, Gennaro Altamura, Florence Le Calvez-Kelm, Daniele Viarisio, Katia Zanier, Martin Müller and 2 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in mSphere, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 22 citations in OpenAlex.

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  5. A splice donor inJournal of virology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Lucia MinoniInternational Agency for Research on Cancer (IARC), World Health Organization, Lyon, France.
Maria Carmen Romero-MedinaInternational Agency for Research on Cancer (IARC), World Health Organization, Lyon, France.
Assunta VenutiInternational Agency for Research on Cancer (IARC), World Health Organization, Lyon, France.
Cécilia SirandInternational Agency for Research on Cancer (IARC), World Health Organization, Lyon, France.
Alexis RobitailleInternational Agency for Research on Cancer (IARC), World Health Organization, Lyon, France.
Gennaro AltamuraDepartment of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Florence Le Calvez-KelmInternational Agency for Research on Cancer (IARC), World Health Organization, Lyon, France.
Daniele ViarisioDeutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.
Katia ZanierEquipe labellisée Ligue, Biotechnologie et signalisation cellulaire UMR 7242, Ecole Supérieure de Biotechnologie de Strasbourg, Illkirch, France.
Martin MüllerDeutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.ORCID 0000-0001-7740-7798
Rosita AccardiInternational Agency for Research on Cancer (IARC), World Health Organization, Lyon, France accardi@iarc.fr tommasinom@iarc.fr.ORCID 0000-0002-5456-8297
Massimo TommasinoInternational Agency for Research on Cancer (IARC), World Health Organization, Lyon, France accardi@iarc.fr tommasinom@iarc.fr.ORCID 0000-0002-0890-8596
Centre international de recherche sur le cancer · FRGerman Cancer Research Center · DEÉcole Supérieure de Biotechnologie de Strasbourg · FRUniversity of Naples Federico II · IT

Funding

World Health Organization 001
6 · The paper itself

Abstract

The beta human papillomaviruses (HPVs) are subdivided into 5 species (beta-1 to beta-5), and they were first identified in the skin. However, the beta-3 species appears to be more highly represented in the mucosal epithelia than in the skin. Functional studies have also highlighted that beta-3 HPV49 shares some functional similarities with mucosal high-risk (HR) HPV16. Here, we describe the characterization of the

Indexed as

AlphapapillomavirusAnimalsCells, CulturedEpithelial CellsHuman papillomavirus 16HumansKeratinocytesMaleMiceMucous MembraneNIH 3T3 CellsOncogene Proteins, ViralPapillomavirus E7 ProteinsSkinOncogene Proteins, ViralPapillomavirus E7 Proteinsbeta-3 and mucosal HPV typeskeratinocyte immortalizationp53 and pRb regulated pathways

Identifiers

PMID32669468
PMCPMC7364212
OpenAlexW3042709572

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.