ArticleFrontiers in physiology2020
Autonomic Control of the Heart and Its Clinical Impact. A Personal Perspective.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Day and night heart rate variability using 24-h ECG recordings: a systematic review with meta-analysis using a gender lens.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023Pooled it
- A randomized clinical trial of omega-3 fatty acid and vitamin D supplementation on electrocardiographic risk profiles.Scientific reports · 2023Trial
- Free-living associations between resting heart rate parameters and cardiometabolic health in adults.Physiological reports · 2026Article
- Correlation between heart rate variability and estradiol, progesterone, and the estradiol/progesterone ratio across menstrual phases in healthy women.Physiological reports · 2026Article
- Multimodal, device-based therapeutic targeting of the cardiovascular autonomic nervous system.Nature reviews. Cardiology · 2026Review
- Acute autonomic modulation during Jacobson's progressive muscle relaxation in normal-weight vs. overweight male recreational athletes.Scientific reports · 2026Article
- Review
- Modelling neurocardiac physiology and diseases using human pluripotent stem cells: current progress and future prospects.The Journal of physiology · 2025Review
- Women with premenstrual syndrome exhibit high interoceptive accuracy, but low awareness, with parasympathetic rebound responses from stress.Frontiers in neuroscience · 2025Article
- Autonomic and baroreflex regulations in syndromic and non-syndromic aortopathies: a case-control study.Frontiers in physiology · 2025Article
- Utility of nonlinear analysis of heart rate variability in early detection of metabolic syndrome.Frontiers in physiology · 2025Article
- Heart Rate Variability During Weaning from Invasive Mechanical Ventilation: A Systematic Review.Journal of clinical medicine · 2024Review
- Impact of surgical aortic valve replacement and transcatheter aortic valve implantation on cardiovascular and cerebrovascular controls: A pilot study.Physiological reports · 2024Article
- Immediate Increase in the Root Mean Square of Successive Differences after Three Bouts of Remote Ischemic Preconditioning: A Randomized Controlled Trial.Journal of cardiovascular development and disease · 2024Article
- Autonomic Function and Baroreflex Control in COVID-19 Patients Admitted to the Intensive Care Unit.Journal of clinical medicine · 2024Article
- Differences in heart rate responses to upright posture are associated with variations in the high-frequency power of heart rate variability.American journal of physiology. Heart and circulatory physiology · 2024Article
- Heart Rate Variability and Cognition: A Narrative Systematic Review of Longitudinal Studies.Journal of clinical medicine · 2024Review
- The contribution of granger causality analysis to our understanding of cardiovascular homeostasis: from cardiovascular and respiratory interactions to central autonomic network control.Frontiers in network physiology · 2024Review
- Linking hearts and minds: understanding the cardiovascular impact of bipolar disorder.Future cardiology · 2024Review
- Data analysis protocol for early autonomic dysfunction characterization after severe traumatic brain injury.Frontiers in neurology · 2024Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This essay covers several aspects of the autonomic control of the heart, all relevant to cardiovascular pathophysiology with a direct impact on clinical outcomes. Ischemic heart disease, heart failure, channelopathies, and life-threatening arrhythmias are in the picture. Beginning with an overview on some of the events that marked the oscillations in the medical interest for the autonomic nervous system, our text explores specific areas, including experimental and clinical work focused on understanding the different roles of tonic and reflex sympathetic and vagal activity. The role of the baroreceptors, not just for the direct control of circulation but also because of the clinical value of interpreting alterations (spontaneous or induced) in their function, is discussed. The importance of the autonomic nervous system for gaining insights on risk stratification and for providing specific antiarrhythmic protection is also considered. Examples are the interventions to decrease sympathetic activity and/or to increase vagal activity. The non-invasive analysis of the RR and QT intervals provides additional information. The three of us have collaborated in several studies and each of us contributes with very specific and independent areas of expertise. Here, we have focused on those areas to which we have directly contributed and hence speak with personal experience. This is not an attempt to provide a neutral and general overview on the autonomic nervous system; rather, it represents our effort to share and provide the readers with our own personal views matured after many years of research in this field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.