ArticleJMIR mHealth and uHealth2020
A Physical Activity and Diet Program Delivered by Artificially Intelligent Virtual Health Coach: Proof-of-Concept Study.
Article in JMIR mHealth and uHealth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07612800 (Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention), which is not on this map. Cited by 78 papers, 9 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Tailored Brain Health Insights Through Nurturing Knowledge-based Change - Stakeholder-driven, Human-centered, AI-powered Refinement for Prevention (THINK-SHARP)
Who cites it
78 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Implementation and Applications of Artificial Intelligence in Nutrition: A Systematic Review of Use in Practice and Research.Nutrients · 2026Pooled it
- Interactive Conversational Agents to Improve Dietary Behaviors for Health Promotion: Mixed Systematic Review.Journal of medical Internet research · 2025Pooled it
- Natural Language Processing Chatbot-Based Interventions for Improvement of Diet, Physical Activity, and Tobacco Smoking Behaviors: Systematic Review.JMIR mHealth and uHealth · 2025Pooled it
- Systematic review exploring human, AI, and hybrid health coaching in digital health interventions: trends, engagement, and lifestyle outcomes.Frontiers in digital health · 2025Pooled it
- Application of Chatbots to Help Patients Self-Manage Diabetes: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Conversational Agents for Body Weight Management: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Artificial Intelligence-Based Chatbots for Promoting Health Behavioral Changes: Systematic Review.Journal of medical Internet research · 2023Pooled it
- A systematic review of artificial intelligence chatbots for promoting physical activity, healthy diet, and weight loss.The international journal of behavioral nutrition and physical activity · 2021Pooled it
- Promoting Physical Activity Through Conversational Agents: Mixed Methods Systematic Review.Journal of medical Internet research · 2021Pooled it
- Feasibility of the "LvL UP" trial: a pilot sequential multiple assignment randomised trial of an adaptive, holistic mHealth lifestyle coaching intervention.The international journal of behavioral nutrition and physical activity · 2026Trial
- A behaviourally informed chatbot increases vaccination rates in Argentina more than a one-way reminder.Nature human behaviour · 2024Trial
- An 8-Week Peer Health Coaching Intervention among College Students: A Pilot Randomized Study.Nutrients · 2023Trial
- Trial
- Long-Term Adherence to a Mediterranean Diet 1-Year after Completion of the MedLey Study.Nutrients · 2022Trial
- Acceptability, usefulness, and satisfaction with a web-based video-tailored physical activity intervention: The TaylorActive randomized controlled trial.Journal of sport and health science · 2022Trial
- Personalization of Training and Weight Reduction Using Artificial Intelligence: A Scoping Review of Current Evidence and Practical Limitations.Journal of functional morphology and kinesiology · 2026Review
- Artificial Intelligence as a Personal Coach: A Narrative Review of Benefits and Risks in Educational and Health Contexts.Behavioral sciences (Basel, Switzerland) · 2026Review
- Review
- Shaping the Future of Men's Health: How AI Could Be a Transformative Tool for Better Patient Outcomes and Provider Efficiency.Journal of medical Internet research · 2026Article
- Mapping behavior change techniques and health data combinations in virtual agents for chronic condition management: A systematic scoping review.PLOS digital health · 2026Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPoor diet and physical inactivity are leading modifiable causes of death and disease. Advances in artificial intelligence technology present tantalizing opportunities for creating virtual health coaches capable of providing personalized support at scale.
objectiveThis proof of concept study aimed to test the feasibility (recruitment and retention) and preliminary efficacy of physical activity and Mediterranean-style dietary intervention (MedLiPal) delivered via artificially intelligent virtual health coach.
methodsThis 12-week single-arm pre-post study took place in Adelaide, Australia, from March to August 2019. Participants were inactive community-dwelling adults aged 45 to 75 years, recruited through news stories, social media posts, and flyers. The program included access to an artificially intelligent chatbot, Paola, who guided participants through a computer-based individualized introductory session, weekly check-ins, and goal setting, and was available 24/7 to answer questions. Participants used a Garmin Vivofit4 tracker to monitor daily steps, a website with educational materials and recipes, and a printed diet and activity log sheet. Primary outcomes included feasibility (based on recruitment and retention) and preliminary efficacy for changing physical activity and diet. Secondary outcomes were body composition (based on height, weight, and waist circumference) and blood pressure.
resultsOver 4 weeks, 99 potential participants registered expressions of interest, with 81 of those screened meeting eligibility criteria. Participants completed a mean of 109.8 (95% CI 1.9-217.7) more minutes of physical activity at week 12 compared with baseline. Mediterranean diet scores increased from a mean of 3.8 out of 14 at baseline, to 9.6 at 12 weeks (mean improvement 5.7 points, 95% CI 4.2-7.3). After 12 weeks, participants lost an average 1.3 kg (95% CI -0.1 to -2.5 kg) and 2.1 cm from their waist circumference (95% CI -3.5 to -0.7 cm). There were no significant changes in blood pressure. Feasibility was excellent in terms of recruitment, retention (90% at 12 weeks), and safety (no adverse events).
conclusionsAn artificially intelligent virtual assistant-led lifestyle-modification intervention was feasible and achieved measurable improvements in physical activity, diet, and body composition at 12 weeks. Future research examining artificially intelligent interventions at scale, and for other health purposes, is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.