Evidence map›Paper›PMID 32676134›Full record

Trial reportPain research & management2020

Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial.

Somayeh Iravani, Amir Hooman Kazemi Motlagh, Seyede Zahra Emami Razavi, Farhad Shahi, Jing Wang, Li Hou, Wenjun Sun, Mohammad Reza Afshari Fard, Mahdi Aghili, Mehrdad Karimi and 2 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pain research & management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05904340 (The Efficacy of Social Media Assisted Home-based Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated with Chemotherapy Induced Peripheral Neuropathy in Patients with Breast Cancer), which is not on this map. Cited by 30 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 7 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05904340 narecruitingnot on this mapstarted 2023, after this paper: background citation

The Efficacy of Social Media Assisted Home-based Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated with Chemotherapy Induced Peripheral Neuropathy in Patients with Breast Cancer

TypeinterventionalSponsorNational Taipei University of Nursing and Health SciencesRan2023 to 2025Enrolled86ConditionsBreast Neoplasms, Chemotherapy-induced Peripheral NeuropathyArmsTranscutaneous Electrical Nerve Stimulation
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 7 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Invasive or noninvasive? A systematic review and network meta-analysis of acupuncture and acupressure to treat cancer pain.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  13. Chronic Pain in the Cancer Survivor.Current pain and headache reports · 2025
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  19. Multimodal Approaches in the Treatment of Chronic Peripheral Neuropathy-Evidence from Germany.International journal of environmental research and public health · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Somayeh IravaniSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID 0000-0003-3539-7936
Amir Hooman Kazemi MotlaghSchool of Persian Medicine, Tehran University of Medical Science, Tehran, Iran.
Seyede Zahra Emami RazaviDepartment of Physical Medicine and Rehabilitation, Imam Khomeini Hospital Complex, Tehran University of Medical Science, Tehran, Iran.ORCID 0000-0001-8121-7217
Farhad ShahiDepartment of Hematology and Medical Oncology, Imam Khomeini Hospital Complex, Cancer Institute Research Center, Tehran University of Medical Science, Tehran, Iran.
Jing WangDepartment of Hematology and Oncology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.ORCID 0000-0002-2735-7283
Li HouDepartment of Hematology and Oncology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China.ORCID 0000-0003-2921-0821
Wenjun SunDepartment of Neurology, 3 Affiliated Hospital, Beijing University of Chinese Medicine, Beijing 100029, China.
Mohammad Reza Afshari FardSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID 0000-0001-9293-4748
Mahdi AghiliDepartment of Radiation Oncology, Radiation Oncology Research Center, Tehran University of Medical Science, Tehran, Iran.ORCID 0000-0002-8150-618X
Mehrdad KarimiSchool of Persian Medicine, Tehran University of Medical Science, Tehran, Iran.ORCID 0000-0001-5395-819X
Hossein RezaeizadehSchool of Persian Medicine, Tehran University of Medical Science, Tehran, Iran.
Baixiao ZhaoSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID 0000-0003-3644-6883
University of Tehran · IRBeijing University of Chinese Medicine · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This pilot study aims to evaluate the effectiveness and safety of acupuncture in the treatment of chemotherapy-induced peripheral neuropathy (CIPN). Methods: This study was a pilot randomized controlled trial, which was conducted with cooperation between Beijing University of Chinese Medicine (BUCM), China, and Tehran University of Medical Science (TUMS), Iran. Forty participants with CIPN were randomly assigned (1 : 1) to receive twelve sessions of acupuncture (20 minutes each session over 4 weeks) or take one 300 mg tablet of vitamin B1 and three 300 mg capsules of gabapentin per day for 4 weeks, after which both groups were followed up for 4 weeks. The primary endpoint was CIPN symptom severity measured by the Numerical Rating Scale (NRS). The secondary endpoints included sensory neuropathy grade evaluated by the National Cancer Institute-Common Toxicity Criteria for Adverse Events (NCI-CTCAE), neurophysiological assessment of CIPN by the nerve conduction study (NCS), and the patient overall satisfaction with treatment. Safety was assessed at each visit. Results: The NRS and NCI-CTCAE sensory neuropathy grading scales decreased significantly over time in both groups (both Conclusion: Our study revealed that acupuncture, as a kind of traditional Chinese therapeutic method, is significantly effective and safe in the treatment of CIPN. Moreover, acupuncture is more effective than using vitamin B1 and gabapentin as the conventional treatment.

Indexed as

Acupuncture TherapyAdultAnalgesicsAntineoplastic AgentsChinaFemaleGabapentinHumansIranMaleMiddle AgedPilot ProjectsPolyneuropathiesSingle-Blind MethodThiamineTreatment OutcomeAnalgesicsAntineoplastic AgentsGabapentinThiamineVitamin B Complex

Identifiers

PMID32676134
PMCPMC7341378
OpenAlexW3037238732

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.