Observational studyJournal of diabetes investigation2021
Prediabetes and long-term outcomes in patients with three-vessel coronary artery disease: A large single-center cohort study.
Observational study in Journal of diabetes investigation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Association of prediabetes and insulin resistance on prognosis of patients with moderate-to-severe coronary artery calcification: a prospective cohort study.Cardiovascular diabetology · 2025Article
- The Importance of Prediabetes Screening in the Prevention of Cardiovascular Disease.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2023Article
- Prognostic value of fibrinogen in patients with coronary artery disease and prediabetes or diabetes following percutaneous coronary intervention: 5-year findings from a large cohort study.Cardiovascular diabetology · 2021Observational
- Long term prognostic implication of newly detected abnormal glucose tolerance among patients with stable cardiovascular disease: a population-based cohort study.Journal of translational medicine · 2021Article
- Prediabetes and long-term outcomes in patients with three-vessel coronary artery disease: A large single-center cohort study.Journal of diabetes investigation · 2021Observational
Corrections and comments
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Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
AIMS/
introductionWhether detection of prediabetes by routinely testing hemoglobin A MATERIALS AND
methodsThis study included 8,891 Chinese patients with three-vessel disease. Patients were categorized according to their glycemic status (normoglycemia [NG], n = 3,195; prediabetes, n = 1,978; diabetes mellitus, n = 3,718).
resultsThe median follow-up time was 7.5 years, during which 1,354 deaths and 2,340 major adverse cardiac and cerebrovascular events occurred. Compared with the NG group, patients in the prediabetes and diabetes mellitus groups had more comorbidities. After adjusting for confounders, the diabetes mellitus group had a higher risk of all-cause death (hazard ratio [HR] 1.36, 95% confidence interval [CI] 1.20-1.53; P < 0.001), cardiac death (HR 1.35, 95% CI 1.14-1.61; P = 0.001) and major adverse cardiac and cerebrovascular events (HR 1.22, 95% CI 1.11-1.34; P < 0.001) compared with the NG group, whereas the prediabetes and NG groups had no significant difference. The diabetes mellitus group also had a higher risk of stroke compared with the NG group (HR 1.22, 95% CI 1.02-1.46; P = 0.031).
conclusionsIn the context of three-vessel disease, prediabetes patients have comparable long-term outcomes in terms of major adverse cardiac and cerebrovascular events, cardiac death and all-cause death to those with NG. Routine screening of glycemic metabolism based on hemoglobin A
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