Evidence map›Paper›PMID 32689947›Full record

ArticleBMC genomics2020

Comparative population genomic analysis uncovers novel genomic footprints and genes associated with small body size in Chinese pony.

Hojjat Asadollahpour Nanaei, Ali Esmailizadeh, Ahmad Ayatollahi Mehrgardi, Jianlin Han, Dong-Dong Wu, Yan Li, Ya-Ping Zhang

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

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  6. Genomic Insights into Post-Domestication Expansion and Selection of Body Size in Ponies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Hojjat Asadollahpour NanaeiDepartment of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman, PB, 76169-133, Iran.
Ali EsmailizadehDepartment of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman, PB, 76169-133, Iran. aliesmaili@uk.ac.ir.ORCID http://orcid.org/0000-0003-0986-6639
Ahmad Ayatollahi MehrgardiDepartment of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman, PB, 76169-133, Iran.
Jianlin HanCAAS-ILRI Joint Laboratory on Livestock and Forage Genetic Resources, Institute of Animal Science, Chinese Academy of Agricultural Sciences (CAAS), Beijing, China.
Dong-Dong WuState Key Laboratory of Genetic Resources and Evolution and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, No. 32 Jiaochang Donglu, Kunming, Yunnan, China.
Yan LiState Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan and Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming, China. liyan0910@ynu.edu.cn.
Ya-Ping ZhangState Key Laboratory of Genetic Resources and Evolution and Yunnan Laboratory of Molecular Biology of Domestic Animals, Kunming Institute of Zoology, Chinese Academy of Sciences, No. 32 Jiaochang Donglu, Kunming, Yunnan, China. zhangyp@mail.kiz.ac.cn.
Shahid Bahonar University of Kerman · IRKunming Institute of Zoology · CNChinese Academy of Agricultural Sciences · CNYunnan University · CN

Funding

CAS Key Laboratory of Receptor Research XDA2004010302Innovative Research Group Project of the National Natural Science Foundation of China (CN) 91531303International cooperation program of bureau of international cooperation of Chinese Academy of Sciences GJHZ1559
6 · The paper itself

Abstract

backgroundBody size is considered as one of the most fundamental properties of an organism. Due to intensive breeding and artificial selection throughout the domestication history, horses exhibit striking variations for heights at withers and body sizes. Debao pony (DBP), a famous Chinese horse, is known for its small body size and lives in Guangxi mountains of southern China. In this study, we employed comparative population genomics to study the genetic basis underlying the small body size of DBP breed based on the whole genome sequencing data. To detect genomic signatures of positive selection, we applied three methods based on population comparison, fixation index (F

resultsA number of protein-coding genes in windows with the top 1% values of F

conclusionsResults of our study identified some positively selected genes across the horse genome, which are possibly involved in body size traits. These novel candidate genes may be useful targets for clarifying our understanding of the molecular basis of body size and as such they should be of great interest for future research into the genetic architecture of relevant traits in horse breeding program.

Indexed as

MetagenomicsSelection, GeneticAnimalsBody SizeChinaGenomicsHorsesPolymorphism, Single NucleotideArtificial selectionBody sizeHorseNELL1Population genomics

Identifiers

PMID32689947
PMCPMC7370493
OpenAlexW3043023760

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.