Evidence map›Paper›PMID 32690362›Full record

ReviewTrends in plant science2020

How Plants Synthesize Pyrethrins: Safe and Biodegradable Insecticides.

Daniel B Lybrand, Haiyang Xu, Robert L Last, Eran Pichersky

Open access · bronzeAbstract readReview
In one paragraph

Review in Trends in plant science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.

  1. Frontiers in pharmacology · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Article
  14. The Invasive Alien PlantPlants (Basel, Switzerland) · 2024
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Effects of insecticides and repellents on the spread of 'Journal of plant diseases and protection : scientific journal of the German Phytomedical Society (DPG) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Daniel B LybrandDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA.
Haiyang XuCenter of Plant Functional Genomics, Institute of Advanced Interdisciplinary Studies, Chongqing University, Chongqing, China.
Robert L LastDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, USA; Department of Plant Biology, Michigan State University, East Lansing, MI, USA.
Eran PicherskyDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA. Electronic address: lelx@umich.edu.
Michigan State University · USChongqing University · CNUniversity of Michigan · US

Funding

Plant Biotechnology for Health and SustainabilityT32GM110523 · NIGMS · MICHIGAN STATE UNIVERSITY · PI LAST, ROBERT LOUIS · 2014 to 2023
$2.2M
NIGMS NIH HHS T32 GM110523
6 · The paper itself

Abstract

Natural pyrethrin insecticides produced by Dalmatian pyrethrum (Tanacetum cinerariifolium) have low mammalian toxicity and short environmental persistence, providing an alternative to widely used synthetic agricultural insecticides that pose a threat to human health and the environment. A recent surge of interest in the use of pyrethrins as agricultural insecticides coincides with the discovery of several new genes in the pyrethrin biosynthetic pathway. Elucidation of this pathway facilitates efforts to breed improved pyrethrum varieties and to engineer plants with improved endogenous defenses or hosts for heterologous pyrethrin production. We describe the current state of knowledge related to global pyrethrum production, the pyrethrin biosynthetic pathway and its regulation, and recent efforts to engineer the pyrethrin pathway in diverse plant hosts.

Indexed as

Chrysanthemum cinerariifoliumInsecticidesPyrethrinsPlant BreedingInsecticidesPyrethrinsnatural insecticidespyrethrinsspecialized metabolismTanacetum cinerariifoliumtrichomes

Identifiers

PMID32690362
PMCPMC7677217
OpenAlexW3043360067

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.