Evidence map›Paper›PMID 32698467›Full record

ArticleBiology2020

Impairments of Synaptic Plasticity Induction Threshold and Network Oscillatory Activity in the Hippocampus Underlie Memory Deficits in a Non-Transgenic Mouse Model of Amyloidosis.

Jennifer Mayordomo-Cava, Guillermo Iborra-Lázaro, Souhail Djebari, Sara Temprano-Carazo, Irene Sánchez-Rodríguez, Danko Jeremic, Agnès Gruart, José María Delgado-García, Lydia Jiménez-Díaz, Juan D Navarro-López

Open access · goldAbstract read
In one paragraph

Article in Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Experimental modeling of Alzheimer's disease: Translational lessons from cross-taxon analyses.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  6. Article
  7. Article
  8. Systematic characterization of a non-transgenic AβBiology of sex differences · 2023
    Article
  9. Article
  10. Amyloid AβInternational journal of molecular sciences · 2022
    Article
  11. Article
  12. Neuronal G protein-gated KAmerican journal of physiology. Cell physiology · 2022
    Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jennifer Mayordomo-CavaNeurophysiology and Behavioral Lab, Centro Regional de Investigaciones Biomédicas, School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0001-6476-1173
Guillermo Iborra-LázaroNeurophysiology and Behavioral Lab, Centro Regional de Investigaciones Biomédicas, School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.
Souhail DjebariNeurophysiology and Behavioral Lab, Centro Regional de Investigaciones Biomédicas, School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.
Sara Temprano-CarazoNeurophysiology and Behavioral Lab, Centro Regional de Investigaciones Biomédicas, School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.
Irene Sánchez-RodríguezNeurophysiology and Behavioral Lab, Centro Regional de Investigaciones Biomédicas, School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0002-7280-9293
Danko JeremicNeurophysiology and Behavioral Lab, Centro Regional de Investigaciones Biomédicas, School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.
Agnès GruartDivision of Neurosciences, Pablo de Olavide University, 41013 Seville, Spain.
José María Delgado-GarcíaDivision of Neurosciences, Pablo de Olavide University, 41013 Seville, Spain.ORCID 0000-0001-7369-4195
Lydia Jiménez-DíazNeurophysiology and Behavioral Lab, Centro Regional de Investigaciones Biomédicas, School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.
Juan D Navarro-LópezNeurophysiology and Behavioral Lab, Centro Regional de Investigaciones Biomédicas, School of Medicine of Ciudad Real, University of Castilla-La Mancha, 13071 Ciudad Real, Spain.ORCID 0000-0002-1877-7833
University of Castilla-La Mancha · ESUniversidad Pablo de Olavide · ES

Funding

Fundación Tatiana Pérez de Guzmán el Bueno LJDMinisterio de Ciencia, Innovación y Universidades BFU2014-56164-P; BFU2017-82494-P; RYC-2009- 03827
6 · The paper itself

Abstract

In early Alzheimer disease (AD) models synaptic failures and upstreaming aberrant patterns of network synchronous activity result in hippocampal-dependent memory deficits. In such initial stage, soluble forms of Amyloid-

Indexed as

Alzheimer modelamyloid-βbehaviorelectrophysiologyhabituationhippocampusin vivoLTDLTPmetaplasticitynovel object recognitionoscillatory activitysynaptic plasticity

Identifiers

PMID32698467
PMCPMC7407959
OpenAlexW3042539691

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.