ReviewObesity (Silver Spring, Md.)2020
Metabolic Implications of Exposure to Light at Night: Lessons from Animal and Human Studies.
Review in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.
- Human melanopsin (OPN4) gene polymorphisms: a systematic review.Frontiers in neuroscience · 2025Pooled it
- Glycemic and sleep effects of daytime compared with those of overnight infusions of home parenteral nutrition in adults with short bowel syndrome: A quasi-experimental pilot trial.The American journal of clinical nutrition · 2024Trial
- Chronic exposure to artificial light at night dampens rhythms in locomotor activity, metabolism, and sleep in female mice.Physiology & behavior · 2026Article
- Association between light exposure patterns and multidimensional health outcomes in individuals with myalgic encephalomyelitis/chronic fatigue syndrome: findings from an observational cross-sectional cohort study.Journal of translational medicine · 2026Observational
- Diurnal Light Exposure and Rest-Activity Rhythms in Relation to MASLD: Insights From 2 Nationwide Cohort Studies.The Journal of clinical endocrinology and metabolism · 2026Article
- GLP-1 Receptor Agonists at the Crossroads of Circadian Biology, Sleep, and Metabolic Disease.International journal of molecular sciences · 2026Review
- The Light-Eye-Brain Axis: Neurobiological Links Between Mood Disorders and Myopia-A Narrative Review.Ophthalmology and therapy · 2026Review
- Wild-Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026Article
- Article
- Mitigating Blue-Light Risk in Display-Based Digital Therapeutics: A Practical Framework to Support Clinical Efficacy.Journal of clinical medicine · 2026Review
- Can Persistent Blue Light Exposure Cause a Molecular Shift in the Vitreous of Rodents?Scientifica · 2026Article
- Circadian Control of Lipid Metabolism.Advances in experimental medicine and biology · 2026Review
- Exposure to artificial lighting at night: from an ecological challenge to a risk factor for glucose dysmetabolism and gestational diabetes? Narrative review.Annals of medicine · 2025Review
- The Effects of Light on Vertebrate Welfare: A Review.Animals : an open access journal from MDPI · 2025Review
- Lifestyle patterns and their associations with overweight and obesity among children aged 4-9 years in the United Arab Emirates.The British journal of nutrition · 2025Article
- The multifaceted impact of circadian disruption on cancer risk: a systematic review of insights and economic implications.Journal of the National Cancer Center · 2025Review
- Naturalight: A controlled illuminated environment to study light exposure impact on behavior and cognition in freely moving rats.HardwareX · 2025Article
- Role of Nighttime Light in the Association Between Air Pollution Exposure and Cardiovascular Disease.Journal of the American Heart Association · 2025Article
- Association between outdoor artificial light at night and metabolic diseases in middle-aged to older adults-the CHARLS survey.Frontiers in public health · 2025Article
- Circadian de(regulation) in physiology: implications for disease and treatment.Genes & development · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lately, the incidence of overweight, obesity, and type 2 diabetes has shown a staggering increase. To prevent and treat these conditions, one must look at their etiology. As life on earth has evolved under the conditions of nature's 24-hour light/dark cycle, it seems likely that exposure to artificial light at night (LAN) would affect physiology. Indeed, ample evidence has shown that LAN impacts many metabolic parameters, at least partly via the biological clock in the suprachiasmatic nucleus of the hypothalamus. This review focuses on the impact of chronic and acute effects of LAN of different wavelengths on locomotor activity, food intake, the sleep/wake cycle, body temperature, melatonin, glucocorticoids, and glucose and lipid metabolism. While chronic LAN disturbs daily rhythms in these parameters, experiments using short-term LAN exposure also have shown acute negative effects in metabolically active peripheral tissues. Experiments using LAN of different wavelengths not only have indicated an important role for melanopsin, the photopigment found in intrinsically photosensitive retinal ganglion cells, but also provided evidence that each wavelength may have a specific impact on energy metabolism. Importantly, exposure to LAN has been shown to impact glucose homeostasis also in humans and to be associated with an increased incidence of overweight, obesity, and atherosclerosis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.