Evidence map›Paper›PMID 32704412›Full record

ReviewTranslational vision science & technology2020

Insights into Systemic Disease through Retinal Imaging-Based Oculomics.

Siegfried K Wagner, Dun Jack Fu, Livia Faes, Xiaoxuan Liu, Josef Huemer, Hagar Khalid, Daniel Ferraz, Edward Korot, Christopher Kelly, Konstantinos Balaskas and 2 more

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 164 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed, 2 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 2 syntheses or guidelines pooled it, 261 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  7. Review
  8. Article
  9. Review
  10. Article
  11. AI agents: a game changer in ophthalmology?Eye (London, England) · 2026
    Article
  12. Article
  13. Review
  14. Retinal imaging for cerebrovascular risk stratification: evidence, limitations, and practical thresholds for the ophthalmologist.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  15. Article
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  18. Endocrine modulation of cortical and retinal baseline perfusion across the menstrual cycle.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
    Article
  19. Review
  20. Article

104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Siegfried K WagnerNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Dun Jack FuNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Livia FaesNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Xiaoxuan LiuDepartment of Ophthalmology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Josef HuemerNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Hagar KhalidNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Daniel FerrazNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Edward KorotNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Christopher KellyGoogle Health, London, UK.
Konstantinos BalaskasNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Alastair K DennistonNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Pearse A KeaneNIHR Biomedical Research Center at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Moorfields Eye Hospital NHS Foundation Trust · GBUniversity College London · GBGoogle (United Kingdom) · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBUniversity of Birmingham · GB

Funding

Department of Health CS-2014-14-023HSRD VA CRE 12-023Medical Research Council MR/T000953/1Medical Research Council MR/T019050/1
6 · The paper itself

Abstract

Among the most noteworthy developments in ophthalmology over the last decade has been the emergence of quantifiable high-resolution imaging modalities, which are typically non-invasive, rapid and widely available. Such imaging is of unquestionable utility in the assessment of ocular disease however evidence is also mounting for its role in identifying ocular biomarkers of systemic disease, which we term

Indexed as

Eye DiseasesNeurodegenerative DiseasesArtificial IntelligenceDiagnostic Techniques, OphthalmologicalHumansRetinaartificial intelligencedeep learningoptical coherence tomography

Identifiers

PMID32704412
PMCPMC7343674
OpenAlexW3006354677

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.