Evidence map›Paper›PMID 32705312›Full record

ReviewAbdominal radiology (New York)2020

MR elastography of liver: current status and future perspectives.

Ilkay S Idilman, Jiahui Li, Meng Yin, Sudhakar K Venkatesh

Open access · greenAbstract readReview
In one paragraph

Review in Abdominal radiology (New York), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Clinical feasibility of accelerated whole liver water TEuropean radiology experimental · 2026
    Article
  9. Article
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  11. Review
  12. Observational
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  15. Article
  16. Color Maps: Facilitating the Clinical Impact of Quantitative MRI.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Ilkay S IdilmanDepartment of Radiology, Mayo Clinic Alix College of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-1913-2404
Jiahui LiDepartment of Radiology, Mayo Clinic Alix College of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0002-4889-0714
Meng YinDepartment of Radiology, Mayo Clinic Alix College of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID http://orcid.org/0000-0001-6778-192X
Sudhakar K VenkateshDepartment of Radiology, Mayo Clinic Alix College of Medicine, Mayo Clinic, Rochester, MN, USA. venkatesh.sudhakar@mayo.edu.ORCID http://orcid.org/0000-0002-7514-1030
Mayo Clinic in Arizona · USMayo Clinic · US

Funding

Comprehensive noninvasive assessment of liver histopathology in nonalcoholic fatty liver disease (NAFLD) via magnetic resonance imaging, cytometry and elastography (MR-ICE)R01EB017197 · NIBIB · MAYO CLINIC ROCHESTER · PI YIN, MENG · 2014 to 2025
$4.3M
Magnetic Resonance ElastographyR37EB001981 · NIBIB · MAYO CLINIC ROCHESTER · PI EHMAN, RICHARD L. · 2016 to 2025
$4.0M
NIBIB NIH HHS R01 EB017197NIBIB NIH HHS R37 EB001981
6 · The paper itself

Abstract

Non-invasive evaluation of liver fibrosis has evolved over the last couple of decades. Currently, elastography techniques are the most widely used non-invasive methods for clinical evaluation of chronic liver disease (CLD). MR elastography (MRE) of the liver has been used in the clinical practice for nearly a decade and continues to be widely accepted for detection and staging of liver fibrosis. With MRE, one can directly visualize propagating shear waves through the liver and an inversion algorithm in the scanner automatically converts the shear wave properties into an elastogram (stiffness map) on which liver stiffness can be calculated. The commonly used MRE method, two-dimensional gradient recalled echo (2D-GRE) sequence has produced excellent results in the evaluation of liver fibrosis in CLD from various etiologies and newer clinical indications continue to emerge. Advances in MRE technique, including 3D MRE, automated liver elasticity calculation, improvements in shear wave delivery and patient experience, are promising to provide a faster and more reliable MRE of liver. Innovations, including evaluation of mechanical parameters, such as loss modulus, displacement, and volumetric strain, are promising for comprehensive evaluation of CLD as well as understanding pathophysiology, and in differentiating various etiologies of CLD. In this review, the current status of the MRE of liver in CLD are outlined and followed by a brief description of advanced techniques and innovations in MRE of liver.

Indexed as

Elasticity Imaging TechniquesLiver DiseasesForecastingHumansLiverLiver CirrhosisMagnetic Resonance Imaging3D MREDamping ratioElasticityLiver fibrosisViscosityVolumetric strain

Identifiers

PMID32705312
PMCPMC7954231
OpenAlexW3044447404

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.