Evidence map›Paper›PMID 32707695›Full record

ArticleJournal of clinical medicine2020

Exercise Training Protects against Atorvastatin-Induced Skeletal Muscle Dysfunction and Mitochondrial Dysfunction in the Skeletal Muscle of Rats.

Dae Yun Seo, Jun-Won Heo, Mi-Hyun No, Su-Zi Yoo, Jeong Rim Ko, Dong-Ho Park, Ju-Hee Kang, Chang-Ju Kim, Su-Jeen Jung, Jin Han and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Food chemistry. Molecular sciences · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Dae Yun SeoDepartment of Physiology, National Research Laboratory for Mitochondrial Signaling, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan 47392, Korea.ORCID 0000-0002-4377-5792
Jun-Won HeoDepartment of Kinesiology, Inha University, Incheon 22212, Korea.ORCID 0000-0002-9921-2753
Mi-Hyun NoDepartment of Kinesiology, Inha University, Incheon 22212, Korea.ORCID 0000-0002-9526-6914
Su-Zi YooDepartment of Kinesiology, Inha University, Incheon 22212, Korea.
Jeong Rim KoDepartment of Physiology, National Research Laboratory for Mitochondrial Signaling, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan 47392, Korea.
Dong-Ho ParkDepartment of Kinesiology, Inha University, Incheon 22212, Korea.ORCID 0000-0003-1863-0652
Ju-Hee KangDepartment of Pharmacology and Medicinal Toxicology Research Center, Inha University School of Medicine, Incheon 22212, Korea.ORCID 0000-0001-5235-8993
Chang-Ju KimDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul 02447, Korea.ORCID 0000-0003-4749-5795
Su-Jeen JungDepartment of Leisure Sports, Seoil University, Seoul 02192, Korea.
Jin HanDepartment of Physiology, National Research Laboratory for Mitochondrial Signaling, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan 47392, Korea.ORCID 0000-0003-1859-3425
Hyo-Bum KwakDepartment of Kinesiology, Inha University, Incheon 22212, Korea.ORCID 0000-0003-0451-4554
Inha University · KRInje University · KRKyung Hee University · KRSeoil University · KR

Funding

This work was supported by Ministry of Education of the Republic of Korea and the National Research Foundation of Korea (2010-002024, NRF-2016R1A2B4014240, NRF-2018R1A2A3074577, NRF-2019S1A5C2A03082727)
6 · The paper itself

Abstract

Statins are used to prevent and treat atherosclerotic cardiovascular disease, but they also induce myopathy and mitochondrial dysfunction. Here, we investigated whether exercise training prevents glucose intolerance, muscle impairment, and mitochondrial dysfunction in the skeletal muscles of Wistar rats treated with atorvastatin (5 mg kg

Indexed as

exercisemitochondriamyopathyskeletal musclestatin

Identifiers

PMID32707695
PMCPMC7408828
OpenAlexW3042570948

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.