Evidence map›Paper›PMID 32707926›Full record

ArticleCells2020

Lysophosphatidic Acid Receptor 5 Contributes to Imiquimod-Induced Psoriasis-Like Lesions through NLRP3 Inflammasome Activation in Macrophages.

Bhakta Prasad Gaire, Chi-Ho Lee, Wondong Kim, Arjun Sapkota, Do Yup Lee, Ji Woong Choi

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Lysophosphatidic Acid Receptor 5 (LPAInternational journal of molecular sciences · 2026
    Article
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  13. The Anti-Atopic Dermatitis Effects ofInternational journal of molecular sciences · 2023
    Article
  14. Etanercept ameliorates psoriasis progression through regulating high mobility group box 1 pathway.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Article
  15. Review
  16. Frontiers in pharmacology · 2023
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bhakta Prasad GaireCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Korea.
Chi-Ho LeeCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Korea.
Wondong KimCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Korea.
Arjun SapkotaCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Korea.
Do Yup LeeDepartment of Agricultural Biotechnology, Center for Food and Bioconvergence, Research Institute for Agricultural and Life Sciences, Seoul National University, Seoul 08826, Korea.
Ji Woong ChoiCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon 21936, Korea.
Gachon University · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pathogenesis of psoriasis, an immune-mediated chronic skin barrier disease, is not fully understood yet. Here, we identified lysophosphatidic acid (LPA) receptor 5 (LPA

Indexed as

AnimalsBone Marrow CellsCells, CulturedDisease Models, AnimalGene Knockdown TechniquesImiquimodInflammasomesLipopolysaccharidesMacrophagesMaleMiceMice, Inbred BALB CMice, Inbred ICRNLR Family, Pyrin Domain-Containing 3 ProteinPsoriasisReceptors, Lysophosphatidic AcidImiquimodInflammasomesLipopolysaccharidesLPAR5 protein, mouseNLR Family, Pyrin Domain-Containing 3 ProteinNlrp3 protein, mouseReceptors, Lysophosphatidic Acidlysophosphatidic acid receptor 5macrophagesNLRP3 inflammasomepsoriasisTCLPA5

Identifiers

PMID32707926
PMCPMC7465035
OpenAlexW3044102776

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.