Evidence map›Paper›PMID 32709292›Full record

GuidelineKidney international2020

Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference.

Marlies Ostermann, Rinaldo Bellomo, Emmanuel A Burdmann, Kent Doi, Zoltan H Endre, Stuart L Goldstein, Sandra L Kane-Gill, Kathleen D Liu, John R Prowle, Andrew D Shaw and 6 more

2 registry-linked trialsAbstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Kidney international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 316 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
316citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06442280 phase4unknown statusstarted 2024, after this paper: background citation

Enhanced Diuresis and Natriuresis in Acute Decompensated Heart Failure Patients Treated With SGLT-2 Inhibitor and High-Dose Furosemide Plus Small-Volume Hypertonic Saline Solution: A Clinical Trial

Ran2024Enrolled544Registered outcomes4Posted comparisons0ConditionsDiabetes Type 2, Heart Failure Acute, Heart Failure With Preserved Ejection Fraction, Heart Failure With Reduced Ejection FractionArmsDapagliflozin Tablet, Furosemide Injection, Hypertonic Saline Solution, 1 Ml
PMID 36607775PMID 21440872PMID 21885793PMID 22980301PMID 26240596PMID 35241246PMID 20607462PMID 15963399PMID 32139695PMID 32970396PMID 34447992other papers from this trial
Open the trial in the graph
NCT04997915 completednot on this map

Acute Kidney Injury in COVID-19 Patients Admitted to the ICU: a Multicenter Cohort Analysis in 9 Large Hospitals in Belgium

TypeobservationalSponsorUniversity Hospital, GhentRan2020 to 2022Enrolled1,286ConditionsCritical Illness, COVID-19 Pneumonia, Acute Kidney InjuryArmsObservational study exploring the epidemiology and outcomes of AKI in critical COVID-19 patients admitted to the ICU
3 · Its place in the literature

Who cites it

316 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
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  4. Pooled it
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  6. Pooled it
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  10. Trial
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  14. Article
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  16. Review
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  20. Review

256 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Marlies OstermannDepartment of Critical Care, King's College London, Guy's & St. Thomas' Hospital, King's College London, London, UK. Electronic address: Marlies.Ostermann@gstt.nhs.uk.
Rinaldo BellomoCentre for Integrated Critical Care, The University of Melbourne, Melbourne, Victoria, Australia.
Emmanuel A BurdmannLaboratório de Investigação Médica 12, Division of Nephrology, University of Sao Paulo Medical School, Sao Paulo, Sao Paulo, Brazil.
Kent DoiDepartment of Emergency and Critical Care Medicine, The University of Tokyo, Tokyo, Japan.
Zoltan H EndrePrince of Wales Hospital and Clinical School, University of New South Wales, Randwick, NSW, Australia.
Stuart L GoldsteinDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA; Department of Pediatrics, Cincinnati Children's Hospital, Cincinnati, Ohio, USA.
Sandra L Kane-GillDepartment of Pharmacy and Therapeutics, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania, USA.
Kathleen D LiuDepartment of Medicine, Division of Nephrology, University of California, San Francisco, San Francisco, California, USA; Department of Anesthesia, Division of Critical Care Medicine, University of California, San Francisco, San Francisco, California, USA.
John R ProwleWilliam Harvey Research Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London, UK.
Andrew D ShawDepartment of Anesthesiology and Pain Medicine, University of Alberta, Edmonton, Alberta, Canada.
Nattachai SrisawatDivision of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Critical Care Nephrology Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Tropical Medicine Cluster, Chulalongkorn University, Bangkok, Thailand; Excellence Center for Critical Care Nephrology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand; Academy of Science, Royal Society of Thailand, Bangkok, Thailand.
Michael CheungKidney Disease: Improving Global Outcomes (KDIGO), Brussels, Belgium.
Michel JadoulCliniques Universitaires Saint Luc, Université Catholique de Louvain, Brussels, Belgium.
Wolfgang C WinkelmayerSelzman Institute for Kidney Health, Section of Nephrology, Department of Medicine, Baylor College of Medicine, Houston, Texas, USA.
John A KellumDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. Electronic address: kellum@pitt.edu.
Conference Participants

Funding

Beta-lactam individualization for critically ill patientsK23AI143882 · NIAID · MAYO CLINIC ROCHESTER · PI BARRETO, ERIN FRAZEE · 2020 to 2024
$986k
Kidney Protection by AMPKIK2BX002912 · VA · MICHAEL E DEBAKEY VA MEDICAL CENTER · PI PAN, JENNY SZU-CHIN · 2017 to 2021
–
BLRD VA IK2 BX002912NIAID NIH HHS K23 AI143882
6 · The paper itself

Abstract

In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the classification and management of acute kidney injury (AKI). The guideline was derived from evidence available through February 2011. Since then, new evidence has emerged that has important implications for clinical practice in diagnosing and managing AKI. In April of 2019, KDIGO held a controversies conference entitled Acute Kidney Injury with the following goals: determine best practices and areas of uncertainty in treating AKI; review key relevant literature published since the 2012 KDIGO AKI guideline; address ongoing controversial issues; identify new topics or issues to be revisited for the next iteration of the KDIGO AKI guideline; and outline research needed to improve AKI management. Here, we present the findings of this conference and describe key areas that future guidelines may address.

Indexed as

Acute Kidney InjuryHumansacute kidney diseaseacute kidney injuryfluid managementnephrotoxicityrenal replacement therapyrisk stratification

Identifiers

PMID32709292
PMCPMC8481001

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.