Evidence map›Paper›PMID 32714484›Full record

ArticleOxidative medicine and cellular longevity2020

Impact on Longevity of Genetic Cardiovascular Risk and Lifestyle including Red Meat Consumption.

Alda Pereira da Silva, Maria do Céu Costa, Laura Aguiar, Andreia Matos, Ângela Gil, J Gorjão-Clara, Jorge Polónia, Manuel Bicho

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Alda Pereira da SilvaEcogenetics and Human Health Unit, Genetics Laboratory, Environmental Health Institute-ISAMB, Faculty of Medicine, University of Lisbon, Av. Professor Egas Moniz, Piso 1C 1649-028 Lisboa, Portugal.ORCID https://orcid.org/0000-0003-4496-2714
Maria do Céu CostaCBIOS-Biosciences Research Center, School of Health Sciences and Technologies, Universidade Lusófona, Campo Grande 376, 1649-024 Lisboa, Portugal.ORCID https://orcid.org/0000-0002-9887-0973
Laura AguiarEcogenetics and Human Health Unit, Genetics Laboratory, Environmental Health Institute-ISAMB, Faculty of Medicine, University of Lisbon, Av. Professor Egas Moniz, Piso 1C 1649-028 Lisboa, Portugal.
Andreia MatosEcogenetics and Human Health Unit, Genetics Laboratory, Environmental Health Institute-ISAMB, Faculty of Medicine, University of Lisbon, Av. Professor Egas Moniz, Piso 1C 1649-028 Lisboa, Portugal.
Ângela GilEcogenetics and Human Health Unit, Genetics Laboratory, Environmental Health Institute-ISAMB, Faculty of Medicine, University of Lisbon, Av. Professor Egas Moniz, Piso 1C 1649-028 Lisboa, Portugal.
J Gorjão-ClaraUniversity Geriatric Unit, Environmental Health Institute-ISAMB, Faculty of Medicine, University of Lisbon, Portugal.
Jorge PolóniaFaculty of Medicine Oporto, Internal Medicine, Hypertension, Clinical Pharmacology, Alameda Prof. Hernâni Monteiro, 4200-319 Oporto, Portugal.
Manuel BichoEcogenetics and Human Health Unit, Genetics Laboratory, Environmental Health Institute-ISAMB, Faculty of Medicine, University of Lisbon, Av. Professor Egas Moniz, Piso 1C 1649-028 Lisboa, Portugal.
University of Lisbon · PTEscola Superior de Saúde Ribeiro Sanches · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular risk (CVR) underlies aging process and longevity. Previous work points to genetic and environmental factors associated with this risk.

objectivesThe aim of this research is to look for any CVR gene-gene and gene-multifactorial/lifestyle interactions that may impact health and disease and underlie exceptional longevity.

methodsA case-control study involving 521 both gender individuals, 253 centenarians (100.26 ± 1.98 years), and 268 controls (67.51 ± 3.25 years), low (LCR,

resultsAntilongevity factors consisted (OR 95% CI,

conclusionsCardiovascular risk-related genetic and multifactorial or predominantly lifestyle aspects and its interactions might influence the aging process and contribute to exceptional longevity in Portuguese centenarians. Besides lifestyle, the activity of nitrite oxide synthase may be one of the main physiologic regulators of cardiovascular protection in the path of longevity.

Indexed as

Heart Disease Risk FactorsCardiovascular DiseasesCase-Control StudiesFemaleHumansLife StyleLongevityMaleRed Meat

Identifiers

PMID32714484
PMCPMC7354649
OpenAlexW3038558811

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.