Evidence map›Paper›PMID 32715317›Full record

ArticlePsychopharmacology2020

BOLD responses to inhibition in cannabis-using adolescents and emerging adults after 2 weeks of monitored cannabis abstinence.

Alexander L Wallace, Kristin E Maple, Alicia T Barr, Krista M Lisdahl

Open access · greenAbstract read
In one paragraph

Article in Psychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alexander L WallaceDepartment of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
Kristin E MapleDepartment of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
Alicia T BarrDepartment of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
Krista M LisdahlDepartment of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI, USA. krista.medina@gmail.com.
University of Wisconsin–Milwaukee · US

Funding

ABCD-USA Consortium: UWM SIte U01DA041025 · NIDA · UNIVERSITY OF WISCONSIN MILWAUKEE · PI Christine L Larson, Krista Maurine Lisdahl · 2017 to 2026
$11.2M
IDEAA: UWM SiteR01DA030354 · NIDA · UNIVERSITY OF WISCONSIN MILWAUKEE · PI LISDAHL, KRISTA MAURINE · 2011 to 2017
$2.7M
Examining the impact of circulating endocannabinoid levels on neurocognition, mood, and early cannabis use in youth enrolled in the ABCD StudyR21DA049109 · NIDA · UNIVERSITY OF WISCONSIN MILWAUKEE · PI HILLARD, CECILIA J, LISDAHL, KRISTA MAURINE · 2019 to 2020
$433k
NIDA NIH HHS R01 DA030354NIDA NIH HHS R01DA030354NIDA NIH HHS R21 DA049109NIDA NIH HHS U01 DA041025NIDA NIH HHS U01DA041025
6 · The paper itself

Abstract

rationalePrevious studies have suggested that chronic cannabis use has been associated with increased blood oxygen level-dependent (BOLD) response during a response inhibition task; however, these studies primarily included males.

objectivesWe investigated whether gender moderated the effects of cannabis use on BOLD response and behavioral performance during a Go-NoGo task in adolescents and young adults following 2 weeks of monitored abstinence.

methodsParticipants included 77 16-26-year olds (MJ = 36, controls = 41). An emotion-based Go-NoGo task required participants to inhibit their response during a calm face. A whole-brain analysis looked at differences between cannabis group, gender, and their interaction.

resultsSignificant greater BOLD responses were observed in cannabis users compared with that in controls in the left frontal cortex, left cingulate cortex, and the left thalamus during correct response inhibitions; gender did not moderate these effects.

conclusionSupporting previous research, cannabis users showed greater BOLD responses in core areas associated with response inhibition during a Go-NoGo task, even after a minimum of 2 weeks of abstinence.

Indexed as

Inhibition, PsychologicalAdolescentAdultBrainEmotionsFemaleHumansMagnetic Resonance ImagingMaleMarijuana UseOxygen ConsumptionTime FactorsYoung AdultAdolescentsCannabisEmerging adultsfMRIGo-NoGoResponse inhibition

Identifiers

PMID32715317
PMCPMC7572837
OpenAlexW3045469877

What Socratic holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.