Metformin × pharmacokinetics & dosing

SynthesisBMJ open diabetes research & care2020

Association between metformin and neurodegenerative diseases of observational studies: systematic review and meta-analysis.

Fan Ping et al.PubMed ↗Full text ↗Publisher ↗

What the trial testedas reported · 966 people · 2020

Range includes no effect

No clear effect on pharmacokinetics & dosing

+4%−8% to +17%

Bigger than 1 in 10 on the map

As reported

OR 1.04, 95% CI 0.92–1.17

Not counted

Probably raised pharmacokinetics & dosing

1.7×1.1× to 2.4×

Bigger than 7 in 10 on the map

As reported

OR 1.66, 95% CI 1.14–2.42

Two numbers in the abstract

the abstract, start to end

of NDs with metformin exposure (OR 1.04, 95% CI 0.92 to 1.17).

users or glitazone users (OR 1.66, 95% CI 1.14 to 2.42).

← favours treatmentfavours comparator →
could be chance
Pharmacokinetics & dosing
OR 1.040.92–1.17
Pharmacokinetics & dosing
OR 1.661.14–2.42
MetforminThiazolidinedionesPharmacokinetics & dosing
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