Evidence map›Paper›PMID 32722032›Full record

ArticleViruses2020

Effect of the Route of Administration of the Vaccinia Virus Strain LIVP to Mice on Its Virulence and Immunogenicity.

Sergei N Shchelkunov, Stanislav N Yakubitskiy, Alexander A Sergeev, Alexei S Kabanov, Tatiana V Bauer, Leonid E Bulychev, Stepan A Pyankov

Open access · goldAbstract readComparative Study
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sergei N ShchelkunovState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Novosibirsk Region, Russia.
Stanislav N YakubitskiyState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Novosibirsk Region, Russia.
Alexander A SergeevState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Novosibirsk Region, Russia.
Alexei S KabanovState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Novosibirsk Region, Russia.
Tatiana V BauerState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Novosibirsk Region, Russia.
Leonid E BulychevState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Novosibirsk Region, Russia.
Stepan A PyankovState Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, Koltsovo 630559, Novosibirsk Region, Russia.
State Research Center of Virology and Biotechnology VECTOR · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mass smallpox vaccination campaign has played a crucial role in smallpox eradication. Various strains of the vaccinia virus (VACV) were used as a live smallpox vaccine in different countries, their origin being unknown in most cases. The VACV strains differ in terms of pathogenicity exhibited upon inoculation of laboratory animals and reactogenicity exhibited upon vaccination of humans. Therefore, each generated strain or clonal variant of VACV needs to be thoroughly studied in in vivo systems. The clonal variant 14 of LIVP strain (LIVP-14) was the study object in this work. A comparative analysis of the virulence and immunogenicity of LIVP-14 inoculated intranasally (i.n.), intradermally (i.d.), or subcutaneously (s.c.) to BALB/c mice at doses of 10

Indexed as

Administration, IntranasalAnimalsAntibodies, NeutralizingAntibodies, ViralCowpox virusFemaleImmunogenicity, VaccineInjections, IntradermalInjections, SubcutaneousMaleMiceMice, Inbred BALB CSmallpox VaccineVacciniaVaccinia virusVirulenceAntibodies, NeutralizingAntibodies, ViralSmallpox Vaccineimmunogenicitysmallpoxvaccinationvaccinia virusvirulence

Identifiers

PMID32722032
PMCPMC7472337
OpenAlexW3043963992

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.