Evidence map›Paper›PMID 32726130›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2020

Stimulus intensity-dependent recruitment of Na

Fei Ru, Nikoleta Pavelkova, Jeffrey L Krajewski, Jeff S McDermott, Bradley J Undem, Marian Kollarik

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Role of NaThe Journal of physiology · 2024
    Article
  2. Article
  3. Contribution of tetrodotoxin-sensitive, voltage-gated sodium channels (NaAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Fei RuJohns Hopkins University School of Medicine, Baltimore, Maryland.
Nikoleta PavelkovaUniversity of South Florida, Morsani College of Medicine, Tampa, Florida.
Jeffrey L KrajewskiLilly Research Laboratories, Indianapolis, Indiana.
Jeff S McDermottLilly Research Laboratories, Indianapolis, Indiana.
Bradley J UndemJohns Hopkins University School of Medicine, Baltimore, Maryland.
Marian KollarikUniversity of South Florida, Morsani College of Medicine, Tampa, Florida.ORCID 0000-0002-9659-5007
Eli Lilly (United States) · USJohns Hopkins University · USUniversity of South Florida · US

Funding

Identification and Activation Mechanisms of Vagal and Spinal Nociceptors in Esophageal MucosaR01DK110366 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI TAYLOR-CLARK, THOMAS EDWARD, YU, SHAOYONG · 2017 to 2020
$1.4M
Ionic and Structural Mechanisms for Sensory Neuromodulation of the EsophagusU01DK116311 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI TAYLOR-CLARK, THOMAS EDWARD · 2017 to 2019
$786k
Vagal nociceptive pathway mediating pain from the esophagusR21DK124894 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI TAYLOR-CLARK, THOMAS EDWARD · 2020 to 2021
$411k
HHS | National Institutes of Health (NIH) SPARC U01 DK116311NIDDK NIH HHS R01 DK110366NIDDK NIH HHS R21 DK124894NIDDK NIH HHS U01 DK116311
6 · The paper itself

Abstract

We investigated voltage-gated sodium channel (Na

Indexed as

Action PotentialsAnimalsBiomechanical PhenomenaEsophagusGuinea PigsMaleNerve Fibers, UnmyelinatedNociceptionPhysical StimulationRNA, MessengerTetrodotoxinVagus NerveVoltage-Gated Sodium Channel BlockersVoltage-Gated Sodium ChannelsRNA, MessengerTetrodotoxinVoltage-Gated Sodium Channel BlockersVoltage-Gated Sodium ChannelsC-fibersesophagusnerve terminalvagus nervevoltage-gated sodium channels

Identifiers

PMID32726130
PMCPMC7654645
OpenAlexW3046140423

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.