Evidence map›Paper›PMID 32726949›Full record

ArticleCells2020

ROS Dependent Wnt/β-Catenin Pathway and Its Regulation on Defined Micro-Pillars-A Combined In Vitro and In Silico Study.

Susanne Staehlke, Fiete Haack, Anna-Christin Waldner, Dirk Koczan, Caroline Moerke, Petra Mueller, Adelinde M Uhrmacher, J Barbara Nebe

Open access · goldAbstract read
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  8. The Pathogenesis of Oxidative Stress-Induced Chloasma and Its Therapeutic Implications.Clinical, cosmetic and investigational dermatology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Susanne StaehlkeDepartment of Cell Biology, Rostock University Medical Center, Schillingallee 69, 18057 Rostock, Germany.ORCID 0000-0002-0251-8263
Fiete HaackModeling and Simulation Group, Institute for Visual and Analytic Computing, University of Rostock, Albert-Einstein-Str. 22, 18059 Rostock, Germany.ORCID 0000-0003-3713-8313
Anna-Christin WaldnerDepartment of Cell Biology, Rostock University Medical Center, Schillingallee 69, 18057 Rostock, Germany.
Dirk KoczanInstitute for Immunology, Core Facility for Microarray Analysis, Rostock University Medical Center, Schillingallee 70, 18057 Rostock, Germany.
Caroline MoerkeDepartment of Cell Biology, Rostock University Medical Center, Schillingallee 69, 18057 Rostock, Germany.
Petra MuellerDepartment of Cell Biology, Rostock University Medical Center, Schillingallee 69, 18057 Rostock, Germany.
Adelinde M UhrmacherModeling and Simulation Group, Institute for Visual and Analytic Computing, University of Rostock, Albert-Einstein-Str. 22, 18059 Rostock, Germany.
J Barbara NebeDepartment of Cell Biology, Rostock University Medical Center, Schillingallee 69, 18057 Rostock, Germany.ORCID 0000-0003-2662-0905
University of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The physico-chemical surface design of implants influences the surrounding cells. Osteoblasts on sharp-edged micro-topographies revealed an impaired cell phenotype, function and Ca

Indexed as

beta CateninComputer SimulationHumansIn Vitro TechniquesReactive Oxygen SpeciesWnt Signaling Pathwaybeta CateninReactive Oxygen Speciescanonical Wnt pathwaygene profilinghuman osteoblastic cellsin silicomicroarraymicro-pillarsreactive oxygen species (ROS)simulationβ-catenin

Identifiers

PMID32726949
PMCPMC7464713
OpenAlexW3044779240

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.