Evidence map›Paper›PMID 32727225›Full record

Trial reportInhalation toxicology2020

Short course gamma tocopherol did not mitigate effects of ozone on airway inflammation in asthmatics.

Allison J Burbank, Michelle L Hernandez, Carole Robinette, Ting Wang, Haibo Zhou, Neil Alexis, William D Bennett, David B Peden

Open access · greenAbstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in Inhalation toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Exploratory analysis of the impact of sex on sputum proteomic response to inhaled wood smoke in humans.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Allison J BurbankDepartment of Pediatrics, Division of Allergy, Immunology, & Rheumatology, University of North Carolina, Chapel Hill, NC, USA.
Michelle L HernandezDepartment of Pediatrics, Division of Allergy, Immunology, & Rheumatology, University of North Carolina, Chapel Hill, NC, USA.
Carole RobinetteCenter for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, NC, USA.
Ting WangDepartment of Biostatistics, Gillings School of Public Health, University of North Carolina, Chapel Hill, NC, USA.
Haibo ZhouDepartment of Biostatistics, Gillings School of Public Health, University of North Carolina, Chapel Hill, NC, USA.
Neil AlexisCenter for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, NC, USA.
William D BennettCenter for Environmental Medicine, Asthma and Lung Biology, University of North Carolina, Chapel Hill, NC, USA.
David B PedenDepartment of Pediatrics, Division of Allergy, Immunology, & Rheumatology, University of North Carolina, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
Phase II studies of gamma tocopherol as an intervention for environmental asthmaR01ES023349 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PEDEN, DAVID B. · 2013 to 2017
$3.7M
IL-1 receptor blockade as a novel treatment for exacerbation of allergic airway responses in humansR01HL135235 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HERNANDEZ, MICHELLE · 2017 to 2021
$2.7M
Statistical Methods for Outcome-Dependent SamplingR01ES021900 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ZHOU, HAIBO · 2013 to 2016
$1.1M
EPA 83578501NHLBI NIH HHS R01 HL135235NIEHS NIH HHS P30 ES010126NIEHS NIH HHS R01 ES021900NIEHS NIH HHS R01 ES023349
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAir PollutantsAntioxidantsAsthmaCross-Over StudiesCytokinesDouble-Blind MethodEosinophiliaFemalegamma-TocopherolHumansInflammationInhalation ExposureLeukocytes, MononuclearLipopolysaccharidesMaleAir PollutantsAntioxidantsCytokinesgamma-TocopherolLipopolysaccharidesOzone

Identifiers

PMID32727225
PMCPMC8015650
OpenAlexW3046294261

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.