Evidence map›Paper›PMID 32727872›Full record

ArticleJournal of virology2020

Alžběta Dostálková, Filip Kaufman, Ivana Křížová, Barbora Vokatá, Tomáš Ruml, Michaela Rumlová

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Retroviruses use different IPNature communications · 2026
    Article
  3. Review
  4. The "basics" of HIV-1 assembly.PLoS pathogens · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Alžběta DostálkováDepartment of Biotechnology, University of Chemistry and Technology, Prague, Prague, Czech Republic.
Filip KaufmanDepartment of Biotechnology, University of Chemistry and Technology, Prague, Prague, Czech Republic.
Ivana KřížováDepartment of Biotechnology, University of Chemistry and Technology, Prague, Prague, Czech Republic.
Barbora VokatáDepartment of Biochemistry and Microbiology, University of Chemistry and Technology, Prague, Prague, Czech Republic.
Tomáš RumlDepartment of Biochemistry and Microbiology, University of Chemistry and Technology, Prague, Prague, Czech Republic.ORCID 0000-0002-5698-4366
Michaela RumlováDepartment of Biotechnology, University of Chemistry and Technology, Prague, Prague, Czech Republic michaela.rumlova@vscht.cz.ORCID 0000-0002-5645-8227
University of Chemistry and Technology, Prague · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proper assembly and disassembly of both immature and mature HIV-1 hexameric lattices are critical for successful viral replication. These processes are facilitated by several host-cell factors, one of which is myo-inositol hexaphosphate (IP6). IP6 participates in the proper assembly of Gag into immature hexameric lattices and is incorporated into HIV-1 particles. Following maturation, IP6 is also likely to participate in stabilizing capsid protein-mediated mature hexameric lattices. Although a structural-functional analysis of the importance of IP6 in the HIV-1 life cycle has been reported, the effect of IP6 has not yet been quantified. Using two

Indexed as

Virus AssemblyAmino Acid Substitutiongag Gene Products, Human Immunodeficiency VirusHIV-1Mutation, MissensePolyelectrolytesPolymersStructure-Activity Relationshipgag Gene Products, Human Immunodeficiency VirusPolyelectrolytesPolymersassemblycapsidHIV-1immatureIP6maturepolyanion

Identifiers

PMID32727872
PMCPMC7527058
OpenAlexW3045584868

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.