ArticleAJNR. American journal of neuroradiology2020
Perivascular Fat Density and Contrast Plaque Enhancement: Does a Correlation Exist?
Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 43 citations in OpenAlex.
- Photon-counting CT characterization of carotid perivascular adipose tissue: a layer-by-layer quantitative analysis. A preliminary analysis in an asymptomatic population.European radiology · 2026Article
- A radiomics model based on CTA subtraction imaging for differentiating symptomatic and asymptomatic carotid plaques: a retrospective study.BMC cardiovascular disorders · 2026Article
- Additive value of perivascular fat density to CT angiography characteristics of carotid plaques in predicting symptomatic carotid plaques.European radiology · 2025Article
- Assessment of perivascular adipose tissue attenuation using dual-layer spectral-detector CTA for identification of symptomatic carotid plaques.Japanese journal of radiology · 2025Article
- The association between carotid artery perivascular fat density and Covert brain infarction following carotid endarterectomy.Neurosurgical review · 2025Article
- Carotid Pericarotid Fat Density: A New Predictor of Recurrent Ischemic Stroke or Transient Ischemic Attack.Journal of atherosclerosis and thrombosis · 2025Article
- Development of a nomogram model using the dual-energy computed tomography angiography parameters of carotid plaque, the vascular lumen, and perivascular fat to predict acute stroke events.Quantitative imaging in medicine and surgery · 2025Article
- Assessment of Attenuation in Pericarotid Fat among Patients with Carotid Plaque and Spontaneous Carotid Dissection.AJNR. American journal of neuroradiology · 2025Article
- Development of a machine learning-based radiomics model of perivascular adipose tissue for predicting stroke risk in patients with asymptomatic carotid stenosis: a multicenter study.Frontiers in radiology · 2025Article
- Pericarotid Fat as a Marker of Cerebrovascular Risk.AJNR. American journal of neuroradiology · 2024Review
- Association between Pericarotid Fat Density and Positive Remodeling in Patients with Carotid Artery Stenosis.Journal of clinical medicine · 2024Article
- Article
- Peri-Carotid Adipose Tissue and Atherosclerosis at Carotid Bifurcation.Journal of cardiovascular development and disease · 2024Article
- Quantifying Carotid Stenosis: History, Current Applications, Limitations, and Potential: How Imaging Is Changing the Scenario.Life (Basel, Switzerland) · 2024Review
- Carotid artery perivascular adipose tissue on magnetic resonance imaging: a potential indicator for carotid vulnerable atherosclerotic plaque.Quantitative imaging in medicine and surgery · 2023Article
- Pericarotid adipose tissue computed tomography attenuation distinguishes different stages of carotid atherosclerotic disease: a cross-sectional study.Quantitative imaging in medicine and surgery · 2023Article
- Computed tomography angiography-based radiomics model to identify high-risk carotid plaques.Quantitative imaging in medicine and surgery · 2023Article
- Article
- Incremental value of enhanced plaque length for identifying intracranial atherosclerotic culprit plaques: a high-resolution magnetic resonance imaging study.Insights into imaging · 2023Article
- Impact of H-Type Hypertension on Pericarotid Adipose Tissue and Plaque Characteristics Based on Computed Tomography (CT) Angiography: A Propensity Score Matching Study.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeInflammatory changes in the fat tissue surrounding the coronary arteries have been associated with coronary artery disease and high-risk vulnerable plaques. Our aim was to investigate possible correlations between the presence and degree of perivascular fat density and a marker of vulnerable carotid plaque, namely contrast plaque enhancement on CTA. MATERIALS AND
methodsOne-hundred patients (76 men, 24 women; mean age, 69 years) who underwent CT angiography for investigation of carotid artery stenosis were retrospectively analyzed. Contrast plaque enhancement and perivascular fat density were measured in 100 carotid arteries, and values were stratified according to symptomatic (ipsilateral-to-cerebrovascular symptoms)/asymptomatic status (carotid artery with the most severe degree of stenosis). Correlation coefficients (Pearson ρ product moment) were calculated between the contrast plaque enhancement and perivascular fat density. The differences among the correlation ρ values were calculated using the Fisher r-to-z transformation. Mann-Whitney analysis was also calculated to test differences between the groups.
resultsThere was a statistically significant positive correlation between contrast plaque enhancement and perivascular fat density (ρ value = 0.6582,
conclusionsThere was a positive association between perivascular fat density and contrast plaque enhancement on CTA. This correlation was stronger for symptomatic rather than asymptomatic patients. Our results suggest that perivascular fat density could be used as an indirect marker of plaque instability.
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