Evidence map›Paper›PMID 32737795›Full record

ArticleTranslational stroke research2021

Associations of Blood Pressure and Carotid Flow Velocity with Brain Volume and Cerebral Small Vessel Disease in a Community-Based Population.

Shao-Yuan Chuang, Pei-Ning Wang, Liang-Kung Chen, Kun-Hsien Chou, Chih-Ping Chung, Chen-Huan Chen, Gary F Mitchell, Wen-Harn Pan, Hao-Min Cheng

Abstract read
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In one paragraph

Article in Translational stroke research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  5. Observational
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  8. Observational
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  11. Energetic hemodynamic parameters in the carotid artery as a strong predictor of cognitive impairment.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
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  14. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shao-Yuan ChuangInstitute of Population Health Science, National Health Research Institute, Miaoli, Taiwan.
Pei-Ning WangDepartment of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan.
Liang-Kung ChenAging and Health Research Center, National Yang-Ming University, Taipei, Taiwan.
Kun-Hsien ChouAging and Health Research Center, National Yang-Ming University, Taipei, Taiwan.
Chih-Ping ChungDepartment of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan.
Chen-Huan ChenDepartment of Medicine, National Yang-Ming University, Taipei, Taiwan.
Gary F MitchellCardiovascular Engineering, Inc., Norwood, MA, USA.
Wen-Harn PanInstitute of Population Health Science, National Health Research Institute, Miaoli, Taiwan.
Hao-Min ChengInstitute of Public Health and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan. hmcheng@vghtpe.gov.tw.ORCID http://orcid.org/0000-0002-3885-6600

Funding

Ministry of Science and Technology, Taiwan MOHW104-TDU-B-211-113-003, MOHW106-TDU-B-211-113001National Yang-Ming University E107F-M01-0501
6 · The paper itself

Abstract

Cerebral small vessel disease (CSVD) is a common finding on brain magnetic resonance imaging (MRI). We previously demonstrated that high blood pressure (BP) and low carotid flow velocity were associated with cerebrovascular disease. However, their associations with brain volume and CSVD remain to be determined. A total of 721 adults (≥ 50 years) from the community-based I-Lan Longitudinal Aging Study were included. Flow velocities at the common (CCA) and internal carotid artery (ICA), including peak systolic velocity (PSV) and end-diastolic velocity (EDV), were measured with Doppler ultrasound. We further detected the presence of CSVD including lacune, microbleed, and white matter hyperintensity (WMH) on brain MRI, which were used to construct a combined CSVD score. General linear regression and logistic regression analysis were exploited to evaluate the association between carotid flow velocity, BP, brain volume, and CSVD. The mean of white matter, gray matter, and WMH volume were 422.2 cm

Indexed as

Cerebral Small Vessel DiseasesWhite MatterBlood PressureBrainHumansMagnetic Resonance ImagingBrain volumeCarotid flow velocityCerebral small vessel diseaseHigh blood pressureLacuneMicrobleedWhite matter hyperintensity

Identifiers

PMID32737795

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.