ArticleERJ open research2020
Prediction of air trapping or pulmonary hyperinflation by forced spirometry in COPD patients: results from COSYCONET.
Article in ERJ open research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01245933 (Impact of Systemic Manifestations/Comorbidities on Clinical State, Prognosis and Utilisation of Health Care Resources in Patients With COPD), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Systemic Manifestations/Comorbidities on Clinical State, Prognosis and Utilisation of Health Care Resources in Patients With COPD
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.
- The efficacy of manual therapy for chronic obstructive pulmonary disease: A systematic review.PloS one · 2021Pooled it
- Is there a correlation between the changes in airway inflammation and the changes in respiratory mechanics after vaping in patients with asthma?World journal of methodology · 2024Trial
- Lung Function and the Risk of Exacerbation in the β-Blockers for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease Trial.Annals of the American Thoracic Society · 2022Trial
- Bridging the Knowledge Gap: Transforming COPD Management Through Lessons from Asthma.Pulmonary therapy · 2026Review
- Associations Between Musculoskeletal Structural Parameters and Pulmonary Function in Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study.Medical sciences (Basel, Switzerland) · 2026Article
- Comprehensive appraisal of lung function in young COPD patients: a single center observational study.BMC pulmonary medicine · 2024Observational
- Rheumatoid arthritis-associated airway disease: longitudinal pulmonary function behavior.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024Article
- Lung Hyperinflation as Treatable Trait in Chronic Obstructive Pulmonary Disease: A Narrative Review.International journal of chronic obstructive pulmonary disease · 2024Review
- FVC/DEuropean journal of medical research · 2023Article
- Functional imaging in asthma and COPD: design of the NOVELTY ADPro substudy.ERJ open research · 2023Article
- [What have we learned from the German COPD cohort COSYCONET and where do we go from here?]Pneumologie (Stuttgart, Germany) · 2023Article
- Gender-specific differences in COPD symptoms and their impact for the diagnosis of cardiac comorbidities.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Article
- FVC, but not FEVScientific reports · 2022Article
- Article
- CNN-based Deformable Registration Facilitates Fast and Accurate Air Trapping Measurements at Inspiratory and Expiratory CT.Radiology. Artificial intelligence · 2022Article
- Air Trapping and the Risk of COPD Exacerbation: Analysis From Prospective KOCOSS Cohort.Frontiers in medicine · 2022Article
- Differences in the Measurement of Functional Residual Capacity Between Body Plethysmographs of Two Manufacturers.International journal of chronic obstructive pulmonary disease · 2022Article
- Hyperinflation and reduced diffusing capacity predict prognosis in SCLC: value of extended pre-therapeutic lung function testing.Therapeutic advances in respiratory diseaseArticle
- Diaphragm Ultrasound is an Imaging Biomarker that Distinguishes Exacerbation Status from Stable Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary diseaseArticle
- Lower Prevalence of Osteoporosis in Patients with COPD Taking Anti-Inflammatory Compounds for the Treatment of Diabetes: Results from COSYCONET.International journal of chronic obstructive pulmonary diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAir trapping and lung hyperinflation are major determinants of prognosis and response to therapy in chronic obstructive pulmonary disease (COPD). They are often determined by body plethysmography, which has limited availability, and so the question arises as to what extent they can be estimated
methodsWe used data from visits 1-5 of the COPD cohort COSYCONET. Predictive parameters were derived from visit 1 data, while visit 2-5 data was used to assess reproducibility. Pooled data then yielded prediction models including sex, age, height, and body mass index as covariates. Hyperinflation was defined as ratio of residual volume (RV) to total lung capacity (TLC) above the upper limit of normal. (ClinicalTrials.gov identifier: NCT01245933).
resultsVisit 1 data from 1988 patients (Global Initiative for Chronic Obstructive Lung Disease grades 1-4, n=187, 847, 766, 188, respectively) were available for analysis (n=1231 males, 757 females; mean±sd age 65.1±8.4 years; forced expiratory volume in 1 s (FEV
conclusionsThe degree of air trapping/hyperinflation in terms of RV/TLC can be estimated in a simple manner from forced spirometry, with an accuracy sufficient for inferring the presence of hyperinflation. This may be useful for clinical settings, where body plethysmography is not available.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.