Evidence map›Paper›PMID 32753508›Full record

ArticlemSystems2020

Formula Diet Alters the Ileal Metagenome and Transcriptome at Weaning and during the Postweaning Period in a Porcine Model.

Ahmed A Elolimy, Charity Washam, Stephanie Byrum, Celine Chen, Harry Dawson, Anne K Bowlin, Christopher E Randolph, Manish K Saraf, Laxmi Yeruva

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Nutrients · 2025
    Article
  3. Human milkFrontiers in nutrition · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ahmed A ElolimyArkansas Children's Nutrition Center, Little Rock, Arkansas, USA.
Charity WashamDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Stephanie ByrumDepartment of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Celine ChenDiet, Genomics & Immunology Laboratory, USDA-ARS Beltsville Human Nutrition Research Center, Beltsville, Maryland, USA.
Harry DawsonDiet, Genomics & Immunology Laboratory, USDA-ARS Beltsville Human Nutrition Research Center, Beltsville, Maryland, USA.
Anne K BowlinArkansas Children's Nutrition Center, Little Rock, Arkansas, USA.
Christopher E RandolphArkansas Children's Research Institute, Little Rock, Arkansas, USA.
Manish K SarafArkansas Children's Nutrition Center, Little Rock, Arkansas, USA.
Laxmi YeruvaArkansas Children's Nutrition Center, Little Rock, Arkansas, USA vlyeruva@uams.edu.ORCID https://orcid.org/0000-0003-4289-9109
Arkansas Children's Nutrition Center · USArkansas Children's Hospital · USBeltsville Human Nutrition Research Center · USUniversity of Arkansas for Medical Sciences · US

Funding

Translational Regulation in Normal Erythropoiesis and Diamond Blackfan AnemiaP20GM121293 · NIGMS · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI Alan Tackett · 2017 to 2026
$27.6M
Extracellular vesicles miRNA cargo induces inflammation during chlamydial infectionR21AI146521 · NIAID · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI FERRUZZI, MARIO G · 2019 to 2020
$422k
NIAID NIH HHS R21 AI146521NIGMS NIH HHS P20 GM121293
6 · The paper itself

Abstract

Exclusive breastfeeding impacts the intestinal microbiome and is associated with a better immune function than is seen with milk formula (MF) feeding in infants and yet with mechanisms poorly defined. The porcine model was used to evaluate the impact of MF on ileum microbial communities and gene expression relative to human milk (HM)-fed piglets. Fifty-two Dutch Landrace male piglets were fed an isocaloric diet of either HM (

Indexed as

breast milkformula milkileal RNA-seqimmune responseinflammationmucosa microbiotaneonates

Identifiers

PMID32753508
PMCPMC7406227
OpenAlexW3047134178

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.