Evidence map›Paper›PMID 32760337›Full record

ArticleFrontiers in neurology2020

Preeclampsia Drives Molecular Networks to Shift Toward Greater Vulnerability to the Development of Autism Spectrum Disorder.

Qinglian Xie, Zhe Li, Yan Wang, Shan Zaidi, Ancha Baranova, Fuquan Zhang, Hongbao Cao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Qinglian XieDepartment of Outpatient, West China Hospital of Sichuan University, Chengdu, China.
Zhe LiMental Health Center and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu, China.
Yan WangDepartment of Outpatient, West China Hospital of Sichuan University, Chengdu, China.
Shan ZaidiSchool of Systems Biology, George Mason University, Fairfax, VA, United States.
Ancha BaranovaSchool of Systems Biology, George Mason University, Fairfax, VA, United States.
Fuquan ZhangDepartment of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Hongbao CaoSchool of Systems Biology, George Mason University, Fairfax, VA, United States.
Sichuan University · CNGeorge Mason University · USNanjing Medical University · CNResearch Centre for Medical Genetics · RUShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia (PE) confers a significant risk for subsequent diagnosis with autism spectrum disorder (ASD), with the mechanisms underlying this observation being largely unknown. To identify molecular networks affected by both PE and ASD, we conducted a large-scale literature data mining and a gene set enrichment analysis (GSEA), followed by an expression mega-analysis in 13 independently profiled ASD datasets. Sets of genes implicated in ASD and in PE significantly overlap (156 common genes;

Indexed as

autismautism spectrum disorderextreme male brain theoryGSEApreeclampsia

Identifiers

PMID32760337
PMCPMC7373751
OpenAlexW3042400174

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.