Evidence map›Paper›PMID 32765837›Full record

ReviewF1000Research2020

The science of safety: complications associated with the use of mechanical circulatory support in cardiogenic shock and best practices to maximize safety.

Navin K Kapur, Evan H Whitehead, Katherine L Thayer, Mohit Pahuja

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04682483 (Cardiogenic Shock Working Group Registry), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04682483 recruitingnot on this map

Cardiogenic Shock Working Group Registry

Typeobservational_patient_registrySponsorTufts Medical CenterRan2017 to 2026Enrolled5,000ConditionsCardiogenic ShockArmsVasopressor, Inotrope, Acute Mechanical Circulatory Support Devices
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 37 citations in OpenAlex.

  1. Cardiogenic Shock and the Role of Critical Care Cardiology: Evidence, Models of Care, and Future Directions.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Navin K KapurThe Cardiovascular Center for Research and Innovation, Tufts Medical Center, Boston, MA, USA.ORCID 0000-0002-8302-6796
Evan H WhiteheadThe Cardiovascular Center for Research and Innovation, Tufts Medical Center, Boston, MA, USA.
Katherine L ThayerThe Cardiovascular Center for Research and Innovation, Tufts Medical Center, Boston, MA, USA.
Mohit PahujaDivision of Cardiology, Detroit Medical Center/Wayne State University School of Medicine, Detroit, MI, USA.ORCID 0000-0002-7276-710X
Tufts Medical Center · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute mechanical circulatory support (MCS) devices are widely used in cardiogenic shock (CS) despite a lack of high-quality clinical evidence to guide their use. Multiple devices exist across a spectrum from modest to complete support, and each is associated with unique risks. In this review, we summarize existing data on complications associated with the three most widely used acute MCS platforms: the intra-aortic balloon pump (IABP), Impella systems, and veno-arterial extracorporeal membrane oxygenation (VA-ECMO). We review evidence from available randomized trials and highlight challenges comparing complication rates from case series and comparative observational studies where a lack of granular data precludes appropriate matching of patients by CS severity. We further offer a series of best practices to help shock practitioners minimize the risk of MCS-associated complications and ensure the best possible outcomes for patients.

Indexed as

Shock, CardiogenicHeart-Assist DevicesHumansIntra-Aortic Balloon PumpingTime FactorsTreatment Outcomeacute mechanical circulatory supportcardiogenic shockecmoimpellaintraaortic balloon pumpSafety review

Identifiers

PMID32765837
PMCPMC7391013
OpenAlexW3046040612

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.