Evidence map›Paper›PMID 32770858›Full record

ReviewJournal of biochemical and molecular toxicology2020

Updated information on new coronavirus disease 2019 occurrence, drugs, and prediction of a potential receptor.

Forouzan Khodaei, Anam Ahsan, Mostafa Chamanifard, Mohammad Javad Zamiri, Mohammad Mehdi Ommati

Abstract readReview
In one paragraph

Review in Journal of biochemical and molecular toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Forouzan KhodaeiDepartment of Bioinformatics, College of Life Sciences, Shanxi Agricultural University, Taigu, China.ORCID http://orcid.org/0000-0001-5950-4930
Anam AhsanShanxi Key Laboratory of Ecological Animal Science and Environmental Veterinary Medicine, College of Animal Science and Veterinary Medicine, Shanxi Agricultural University, Taigu, China.ORCID https://orcid.org/0000-0002-9398-7128
Mostafa ChamanifardDepartment of Medical Radiation and Nuclear Engineering, Shiraz University, Shiraz, Iran.ORCID https://orcid.org/0000-0002-9408-4238
Mohammad Javad ZamiriDepartment of Animal Science, College of Agriculture, Shiraz University, Shiraz, Iran.ORCID https://orcid.org/0000-0002-3191-5313
Mohammad Mehdi OmmatiDepartment of Bioinformatics, College of Life Sciences, Shanxi Agricultural University, Taigu, China.ORCID https://orcid.org/0000-0003-0514-2414

Funding

Shanxi agriculture university 2018YJ33 and K271999031
6 · The paper itself

Abstract

The new coronavirus (COVID-19) was first reported in Wuhan in China, on 31 December 2019. COVID-19 is a new virus from the family of coronaviruses that can cause symptoms ranging from a simple cold to pneumonia. The virus is thought to bind to the angiotensin-converting enzyme 2, as a well-known mechanism to enter the cell. It then transfers its DNA to the host in which the virus replicates the DNA. The viral infection leads to severe lack of oxygen, lung oxidative stress because of reactive oxygen species generation, and overactivation of the immune system by activating immune mediators. The purpose of this review is to elaborate on the more precise mechanism(s) to manage the treatment of the disease. Regarding the mechanisms of the virus action, the suggested pharmacological and nutritional regimens have been described.

Indexed as

COVID-19 Drug TreatmentAge FactorsAngiotensin-Converting Enzyme 2AntioxidantsAntiviral AgentsCOVID-19Dietary SupplementsHumansImmunologic FactorsIranMedicine, Chinese TraditionalMutationSARS-CoV-2ACE2 protein, humanAngiotensin-Converting Enzyme 2AntioxidantsAntiviral AgentsImmunologic FactorsACE2COVID-19immune mediatorsinhibitory mechanismspneumonia

Identifiers

PMID32770858
PMCPMC7435514

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.